摘要
目的分析生长抑素应用于老年急性糜烂出血性胃炎大出血患者治疗中的临床效果。方法选取我院收治的130例老年急性糜烂出血性胃炎大出血患者为研究对象,随机分为对照组与观察组,各65例。对照组患者进行抑酸、补液、止血等常规治疗,观察组患者在常规治疗基础上添加生长抑素治疗,观察比较两组患者治疗总有效率、48 h与72 h内止血率、1周内出血复发率及不良反应发生率。结果对照组治疗总有效率为78.46%,明显低于观察组的95.38%(P<0.05);对照组48 h内止血率为55.38%,72 h内止血率为75.38%,均低于观察组的72.31%、96.92%,1周内出血复发率(15.38%)较观察组(1.54%)高,差异均具有统计学意义(P<0.05);对照组患者不良反应总发生率(13.85%)明显高于观察组(3.08%),差异具有统计学意义(P<0.05)。结论生长抑素对老年急性糜烂出血性胃炎大出血患者治疗效果显著,适合在临床治疗中推广应用。
Objective To analyze the clinical effect of somatostatin on elderly patients with acute erosive hemorrhagic gastritis. Methods One hundred and thirty elderly patients with acute erosive hemorrhagic gastritis were selected as study objects, all the patients were randomly divided into control group and observation group, with 65 cases in each group. The control group was treated with conventional therapy of acid inhibition, fluid infusion and hemostasis, while the patients in the observation group added with somatostatin based on the control group. The total effective rate, hemostasis rate within 48 hours and 72 hours, recurrence rate of hemorrhage within 1 week and incidence rate of adverse reactions of the two groups were observed and compared. Results The total effective rate of the control group was 78.46%, which was significantly lower than 95.38% of the observation group （P〈0.05）. The hemostasis rate within 48 hours and 72 hours of the control group were respectively 55.38% and 75.38%, which were lower than 72.31% and 96.92% of the observation group; the recurrence rate of hemorrhage within 1 week of the control group was 15.38%, which was significantly higher than 1.54% of the observation group （P〈0.05）. The incidence rate of adverse reactions of the control group was 13.85%, which was significantly higher than 3.08% of the observation group （P〈0.05）. Conclusion Somatostatin on elderly patients with acute erosive hemorrhagic gastritis has significant clinical effect, which is worthy of clinical popularization and application.
出处
《临床医学研究与实践》
2017年第8期22-23,共2页
Clinical Research and Practice
