摘要
目的:探讨采用氟西汀结合眼针干预对急性脑梗死患者神经功能、血糖及PSGL-1水平的影响,分析患者神经功能、血糖及PSGL-1缓解程度间相互关系。方法:病例均来自我院治疗的急性脑梗死患者153例,按随机对照原则分组,对照组72例采用在常规治疗的基础上,采用氟西汀干预治疗,研究组81例在采用在常规治疗的基础上,用氟西汀结合眼针干预治疗,根据脑血管病学术会议制定临床疗效评定标准评价临床效果,对比患者治疗前后PSGL-1、FPG、HbA1c水平及NIHSS评分,采用pearson相关分析治疗前后PSGL-1、FPG、HbA1c及NIHSS评分改善程度间的相关性。结果:虽然对照组治疗有效率84.72%低于研究组治疗有效率91.36%,但无差异(P>0.05);2组治疗前后PSGL-1、FPG、HbA1c水平及NIHSS评分均显著降低(P<0.01),2组治疗后PSGL-1、FPG、HbA1c水平及NIHSS评分无差异(P>0.05);所有患者治疗前后PSGL-1、FPG、HbA1c及NIHSS评分改善程度两两间均存在显著正相关(P<0.01);2组患者不良反应上无差异(P>0.05)。结论:急性脑梗死患者神经功能、血糖及PSGL-1水平关系密切,在氟西汀基础上采用眼针干预治疗,在降低血糖水平及缓解神经功能上效果不显著。
Objective： To explore the effect of fluoxetine combined with eye acupuncture on neurological function, blood glucose and PSGL-1 levels in patients with acute cerebral infarction, and to analyze the relationship between neurological function, blood glucose and PSGL-1 level. Methods： Cases were to self hospital treatment of 153 cases of acute cerebral infarction patients, according to the principle of random control group, 72 cases of the control group with conventional treatment on the basis of the use of fluoxetine in the treatment of intervention, 81 cases in the study group in the conventional treatment based on by fluoxetine combined ocular acupuncture therapy. According to the clinical effect of PSGL-1, HbAlc, FPG and NIHSS before and after treatment, the correlation between PSGL-1, HbAlc, FPG and NIHSS score were compared. Results： The effective rate of control group was 84. 72% lower than that of the study group （P 〉0. 05） ; The two groups of patients before and after treatment PSGL-1, FPG, HbAlc levels and NIHSS scores were significantly lower （P 〈 0.01 ）, the study group after treatment NIHSS score lower than the control group （ P 〈 0.05 ）, and all patients were treated with FPG, HbA1c, HbA1c and NIHSS score improved significantly （P 〈0.01 ） . Conclusion： The effect of eye acupuncture on reducing blood glucose level was not significant, and the improvement of nerve function was related to the improvement of nerve function.
出处
《成都中医药大学学报》
2017年第1期56-59,共4页
Journal of Chengdu University of Traditional Chinese Medicine
关键词
氟西汀
眼针干预
急性脑梗死
神经功能
PSGL-1
Fluoxetine
Eye acupuncture intervention
Acute cerebral infarction
Neurological function
PSGL-1
