摘要
间充质干细胞(mesenchymal stem cells,MSCs)是一种具有全能干细胞特点来源于中胚层发育的早期细胞,具有多向分化的潜能,在特定的诱导条件下可分化为多种细胞。目前,随着MSCs在治疗自身免疫性疾病方面研究日渐深入,越来越多的学者致力于MSCs对干眼的免疫治疗作用的研究。干眼发病率逐年增高,免疫相关性干眼治疗期长,且效果欠佳,影响人们生活质量,迫切需要开发新型治疗方法。因此本文主要就MSCs对干眼治疗方面做系统的综述。
Mesenchymal stem cells （MSCs） are multipotent stromal cells derived from the mesoderm that can differentiate into a variety of cell types. Recently, as the study of MSCs in the treatment of various autoimmune diseases is maturing, more and more researchers have advocated the immune function of MSCs and the treatment for dry eye. The rate of dry eye is higher. The duration of therapy in dry eye, especially immune related dry eye, is long, and the therapeutic effect is poor. Dry eye has affected people＇ s quality of life, so it is important to find new methods to treat it. This article reviews MSCs function in dry eye.
作者
张琛
路晓晓
粘红
魏瑞华
ZHANG Chen LU Xiao-Xiao NIAN Hong WEI Rui-Hua
出处
《眼科新进展》
CAS
北大核心
2017年第3期289-292,共4页
Recent Advances in Ophthalmology
基金
国家自然科学基金资助(编号:81100646)~~
关键词
间充质干细胞
干眼
免疫抑制
mesenchymal stem cells
dry eye
immunosuppression
