摘要
目的分析新生儿呼吸机相关性肺炎(VAP)感染危险因素。方法采用前瞻性研究,以广西横县人民医院及妇幼保健院新生儿重症监护室(NICU)呼吸机通气的417例新生儿作为研究对象,根据通气后48 h是否发生VAP,分为VAP组(132例)和对照组(285)例,采用Logistic回归分析VAP感染的危险因素。结果多因素非条件Logistic回归分析显示,早产儿、原发疾病为肺内疾病、呼吸机通气时间≥5 d、出生时体重<2.5 kg和多次气管内吸引与新生儿VAP相关(P<0.05)。结论新生儿VAP是内因和外因共同作用的结果,应重点加强对早产儿和低出生体重儿的防护。
Objective To analyze the neonatal ventilator associated pneumonia （VAP） infection risk factors, to provide theoretical basis for effective preventive measures.Methods Used the prospective study, 417 cases of neonatal ventilator ventilation as the research object were selected in the Hengxian People＇s Hospital and Hengxian Maternal and Child Healthcare hospital in January 2013-March 2016 neonatal intensive medicine （NICU） , 48 h after the ventilation to take sputum culture and blood tests, chest X-ray examination, after 48 h or 132 cases of VAP as the infection group, 285 cases did not happen the VAP as the control group, by using single factor and Logistic regression analysis of risk factors for infection. Results Multiple factor non conditional logistic regression analysis showed that, the occurrence of neonatal VAP risk factors： premature infants, primary disease to lung diseases, ventilator time more than 5 days, birth weight 〈2.5kg, multiple endotracheal attract （P〈0.05）. Conclusions VAP in neonates is a result of the effect of internal and external factors and main risk factors, premature and low birth weight infants should be strengthened the prevention and control.
作者
姜立双
张海珠
谢宏柳
Jiang Lishuang et al(Neonatal Department, Hengxian People＇s Hospital, Hengxian 530300, Chin)
出处
《齐齐哈尔医学院学报》
2016年第34期4310-4312,共3页
Journal of Qiqihar Medical University
关键词
婴儿
新生
肺炎
呼吸机相关性
危险因素
Infant, newborn
Pneumonia
Ventilator-associated
Risk factors
