摘要
目的评价超声引导下16G空芯针穿刺活检对乳腺病灶诊断的准确性。方法在这项回顾性研究中,我们对693例女性患者的732个病灶进行超声引导下16G空芯针穿刺活检及随后的开放性手术。开放性手术的病理结果作为最终结果(金标准)。分别评估总体和三个亚组(≤1cm、≤2cm、>2cm)的符合率、高危低估率、导管原位癌低估率、漏诊率、敏感性、特异性和假阴性率。结果 732个乳腺病灶的穿刺活检病理结果中恶性占66%,高危病灶占4%,良性占30%。总体穿刺的符合率为97.1%(711/732),低估率2.7%(20/732),假阴性率0.2%(1/493)。三个亚组(≤1cm组、≤2cm组、>2cm组)的符合率、低估率、漏诊率、敏感性、特异性和假阴性率均无显著差异(P>0.05)。结论对于评估乳腺病灶,超声引导下16G空芯针穿刺活检是一种准确的技术方法。对于穿刺活检病理为高危的病例,因存在相对较高的低估率,开放性手术是必要的。
Objective The objective of our study was to determine the diagnostic accuracy of sonographic guided 16-gauge core needle biopsy for breast masses. Methods In this retrospective study, we included a total of 732 lesions from 693 women who had underwent sonographic guided 16-gauge core needle biopsy and subsequent open surgery biopsy. The pathologic results were considered to be the final results（golden standard）. The agreement rate, high-risk underestimate rate, ductal carcinoma in situ （DCIS） underestimate rate, missing rate, sensitivity, specificity, and false- negative rate were assessed in total and three sub-groups（ ≤1cm,（1,2]cm,〉2cm）. Results The pathological results of the core needle biopsies were malignant in 66%, high risk in 4%, and benign in 30%. The agreement rate was 97.1% （711 of 732）. The underestimate rate was 2.7% （20 of 732）. The false-negative rate was 0.2% （1 of 493）. There was no difference between the three sub-groups（≤1cm,（1,2]cm,〉2cm） in agreement rate or underestimate rate or missing rate or sensitivity or specificity or false-negative rate（P〉0.05）. Conclusion Sonographic guided 16-gauge core needle biopsy is an accurate method for evaluating breast masses.Because of relatively high underestimate rate,it is necessary to undergo subsequent open surgery biopsy for the lesions whose pathologic results from the core needle biopsies are high-risk.
出处
《北京医学》
CAS
2017年第1期55-59,共5页
Beijing Medical Journal
关键词
乳腺活检
乳腺肿瘤
空芯针活检
超声引导下乳腺活检
breast biopsy
breast neoplasms
core needle biopsy
sonographically guided breast biopsy
