摘要
目的:探讨超声造影时间-强度曲线与声脉冲辐射力成像(ARFI)在小肝癌诊断中的应用研究。方法:32例肝右叶小肝癌患者纳入研究,癌灶与灶旁实质区同步进行超声造影时间强度曲线分析及ARFI检查。造影定量分析应用Contrast Dynamic软件脱机分析。ARFI检查分别测量病灶区域和同一深度肝脏实质的VTQ值,并进行统计学分析。结果:32例小肝癌灶与灶旁实质区肝组织的Peak、TP和VTQ值均有统计学差异(P<0.05)。肝癌病灶VTQ值与超声造影参数Peak呈正相关(r=0.612,P<0.05)。ROC曲线分析示肝癌病灶Peak38.95%时特异性为65.6%,敏感性为73.7%,曲线下面积为0.789,可信区间为0.685~0.894。结论:ACQ时间强度曲线分析的Peak与声脉冲辐射力成像测得的VTQ值可对小肝癌诊断提供依据,并且两者间具有很好的相关性。
Purpose： To discuss the time-intensity radiation force impulse （ARFI） in diagnosis of small curve of contrast-enhanced ultrasound and virtual acoustic hepatocellular carcinoma （sHCC）. Methods： Time-intensity curve of contrast-enhanced ultrasound and ARFI technical inspection were conducted for the lesion on right liver lobe and parenchymal area around the lesion in 32 cases. Quantitative analysis on contrast-enhanced ultrasonography was conducted by Contrast Dynamic analysis software off line. In ARFI technical inspection, region of interest （ROI） was set in the lesion. By pressing update button, the instrument automatically calculated the VTQ value reflecting shear wave velocity and detected the VTQ value of liver parenchyma in the same depth for statistical analysis. Results： There were statistical significant differences （P〈0.05） of Peak, TP, and VTQ value between lesion in sHCC and parenchymal area around lesion in 32 cases. VTQ value of hepatocellular carcinoma lesion was shown with positive correlation with the peak of contrast-enhanced ultrasound parameters （r=0.612, P〈0.05）. The analysis of ROC curve showed that when the peak of HCC focus was set as 38.95%, the specificity was 65.6%, the sensitivity was 73.7%, the area under curve was 0.789, and the credibility interval was 0.685-0.894. Conclusions： The diagnosis of sHCC can be based on the Peak in ACQ time-intensity curve and VTQ value measured by elasticity imaging techniques. In addition, these two parameters have good correlation between each other.
出处
《中国医学计算机成像杂志》
CSCD
北大核心
2017年第1期82-85,共4页
Chinese Computed Medical Imaging
关键词
小肝癌
超声造影
时间强度曲线
声脉冲辐射力成像
VTQ
Small hepatocellular carcinoma （SHCC）
Contrast-enhanced ultrasound
Time-intensity curve
Acoustic radiation force impulse （ARF1）
VTQ
