摘要
对治疗老年黄斑变性病的药物制剂进行综述。介绍了老年黄斑变性病国内外发病的情况,治疗所使用的药物的剂型情况以及治疗老年黄斑变性病的药物未来研究开发的方向。老年黄斑变性病是全球第三大致盲性疾病,其发病增长率为6.62%。传统药物多是口服而起到全身作用的制剂,新型药物多为局部给药制剂。中医药在治疗老年黄斑变性病方面具有一定的优势,如能与新型制剂技术相结合开发一些局部给药制剂,未来发展前景良好。
In this review,the authors summarized the drugs in treatment of the age-related macular degeneration（ AMD or ARMD）,including the pathogenesis of the age-related macular degeneration at home and abroad,dosage forms used in the treatment,and the drugs research and development directions in the future. AMD disease is the third largest blinding diseases all over the world,with an incidence of 6. 62%. The dosage form of the traditional medicine is mostly oral formulations,playing a role in body,while the newly dosage form is topical drug delivery formulation. Traditional Chinese medicine（ TCM） has certain advantages in the treatment of AMD disease and the development of topical drug delivery preparations with newly preparation technologies would have a very bright prospect in the future.
作者
杜茂波
刘淑芝
许凯
梁丽娜
何爱萍
姚瑶
刘亚梅
DU Mao-bo LIU Shu-zhi XU Kai LIANG Li-na HE Ai-ping YAO Yao LIU Ya-mei(Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China Eye Hospital, China Academy of Chinese Medical Sciences, Beijing 100040, China)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2017年第4期628-633,共6页
China Journal of Chinese Materia Medica
基金
国家自然科学基金项目(81373977)
关键词
老年黄斑变性病
制剂形式
眼科
中医药
age-related macular degeneration（AMD）
drug dosage forms
ophthalmology
traditional Chinese medicine（TCM）
