摘要
体外消化模型是代替体内研究食物蛋白消化的一种重要手段,具有简单易行、可复制等优点。然而体外消化效率受样本类型及消化条件的影响显著,如何更准确的模拟体内生理环境和消化过程,是建立体外消化模型的关键。本文详细介绍了目前已建立的不同类型的食物蛋白质体外消化模型,包括静态模型和动态模型、单室模型和多室模型、单酶体系及多酶体系消化模型,并分析比较其优缺点及适用范围,为根据不同研究目的选择恰当的消化模型提供理论参考,并为标准化体外消化模型提供支撑。
The in vitro digestion model is an important approach to investigate food protein digestion in vivo. It is convemente and reproducible.However, the efficiency in vitro digestion is significantly affected by the sample type and digestion conditions. How to simulate the physiological environment and digestion process more accurately is the key to establish the in vitro digestion model.This review stated the types of in vitro digestion models of food proteins in detail, including static model and dynamic model, monocompartmental model and multicompartmental model, single-enzyme model and multi-enzyme system digestion model.The scope of application and the distinction of the different types of in vitro digestion were also illustrated.This review can be a reference for researchers to select appropriate digestion model, and can help to establish standardization for in vitro digestion models.
作者
游义娇
佟平
袁娟丽
陈红兵
高金燕
YOU Yi-jiao TONG Ping YUAN Juan-li CHEN Hong-bing GAO Jin-yan(State Key Laboratory of Food Science and Technology,Nanchang University,Nanchang 330047, China School of Life Sciences and Food Engineering, Nanchang University, Nanchang 330047, China Sino- German Joint Research Institute, Nanehang University, Nanehang 330047, China)
出处
《食品工业科技》
CAS
CSCD
北大核心
2017年第6期381-385,共5页
Science and Technology of Food Industry
基金
科技部国际合作与交流项目(2013GR0367)
国家自然科学基金(31660436)
江西省自然科学基金计划(重点项目)(20133ACB20009)
江西省国际合作项目(20111BDH80026)
食品科学与技术国家重点实验室目标导向课题(SKLF-ZZA-201612)
关键词
体外消化
消化模型
蛋白质消化
in vitro digestion
digestion model
protein digestion
