摘要
目的探讨阿替普酶溶栓治疗对急性脑梗死患者神经功能及不良反应的影响。方法选取我院2012年9月至2015年12月收治的60例急性脑梗死患者,随机分为研究组和常规组,每组30例。常规组给予基础治疗和阿司匹林口服治疗,研究组给予阿替普酶静脉溶栓治疗。分析比较两组患者的神经功能、不良反应情况以及生活能力。结果研究组的总有效率和治疗后1、3、6个月的ADL评分均明显高于常规组(P<0.05),但两组患者的不良反应发生率比较差异无统计学意义(P>0.05)。结论阿替普酶溶栓治疗可有效改善急性脑梗死患者的神经功能,具有良好的安全性,有利于患者生活能力的恢复。
Objective To explore the effect of alteplase thrombolytic treatment on neural fimction and adverse reactions of patients with acute cerebral infarction. Methods 60 cases of patients with acute cerebral infarction admitted to our hospital from September 2012 to December 2015 were selected and randomly divided into study group and conventional group, with 30 cases in each group. The conventional group received basic treatment and oral aspirin, while the study group received alteplase intravenous thrombolytic treatment. The neural function, adverse reactions and viability were analyzed and compared between two groups. Results The total effective rate and ADL scores for 1, 3 and 6 months after treatment of study group were significantly higher than those of conventional group （P 〈0.05）. No statistical difference was found in the incidence of adverse reactions between two groups （P〉0.05）. Conclusions Alteplase thrombolytic treatment can effectively improve neural function of patients with acute cerebral infarction with good safety, which helps to restore patients＇ viability.
出处
《临床医学工程》
2017年第3期379-380,共2页
Clinical Medicine & Engineering
关键词
阿替普酶
急性脑梗死
神经功能
不良反应
Alteplase
Acute cerebral infarction
Neural function
Adverse reactions
