摘要
光学显微镜的出现为细胞等微观结构的研究打开了新的大门,然而衍射极限的限制使得更加精细的结构难以探测。近年来,一些充满创造性的方法突破了衍射极限,达到纳米级分辨率。氮-空位(NV)色心是金刚石中一种常见的发光缺陷,由于其具有明亮而稳定的发光性质和较长的电子自旋相干时间而被广泛应用于量子计算与量子测量中;同时,NV色心在超分辨成像技术中也发挥着巨大作用,通过与各种超分辨成像显微镜的结合,实现了对NV色心的纳米级分辨率成像,而且进一步实现高空间分辨率的量子传感。本文简单介绍了NV色心的结构与性质,以及各类成像技术的基本原理;对NV色心与超分辨成像结合的各项技术实验成果进行了归纳与比较,并对其应用进行了总结与展望。
The emergence of optical microscopes opens new doors for the study of cell structures. However, the diffraction limit restricts the detection of fine structures. Recent years, a variety of methods are proposed to overcome the diffraction limit and reach the nanoscale resolution. The nitrogen-vacancy (NV) color center, an important defect in diamond with bright and stable luminescence and long electron spin coherence time, is widely used in quantum computation and quantum measurement. At the same time, it also plays a significant role in super- resolution microscopies. The NV center nanoscale resolution imaging is realized with the combination of all kinds of super resolution imaging microscope, and further the quantum sensor of high spatial resolution is realized. A brief introduction to the structure and the property of NV centers and basic principles of the imaging techniques are given simply. The experimental results of the super-resolution imaging with NV centers are summarized and compared, and finally its applications are summarized and prospected in the future.
出处
《激光与光电子学进展》
CSCD
北大核心
2017年第3期25-32,共8页
Laser & Optoelectronics Progress
基金
国家自然科学基金(11374290
91536219
61522508
11504363)
中国博士后科学基金会(2016T90565)
关键词
成像系统
超分辨成像
衍射极限
NV色心
荧光显微镜
imaging systems
super-resolution microscopy
diffraction limit
NV center
fluorescence microscopy