摘要
联合肝脏离断和门静脉结扎的两阶段肝切除术(associating liver partition and portal vein ligation for staged hepatectomy,ALPPS)是近几年提出的一种全新手术方式,因其能显著促进肝组织增生,明显缩短两次手术时间间隔,所以可用于剩余正常肝脏体积不足,不能接受大范围切除的中晚期肝癌病人。目前该术式仍存在风险和难点,有着较高的并发症发生率和病死率,短期效果尚可,但其所带来的长期存活获益尚无定论,故其发展一直伴随着诸多的争议。本文就ALPPS的相关应用进展等作一综述。
The associating liver partition and portal vein ligation for staged hepatectomy （AL- PPS） is a novel method for treating metastatic hepatocellular carcinoma with tremendous or multiple tumors without liver cirrhosis that reported in 2012, the aim of which is to obtain a more rapid and ef- fective increase in future liver remnant （FLR）, so it is suitable for the treatment of liver tumor in which the remaining liver volume is not enough to accept a wide range liver resection. But there are still some problems： a high morbidity and a concerning high mortality. The short-term outcome of ALPPS is fair, but its long-term effect is indeterminate, which leads to a lot of controversy in the development of ALPPS. This article makes an effort to summarize the application and progress of ALPPS.
出处
《腹部外科》
2017年第1期69-72,共4页
Journal of Abdominal Surgery
关键词
肝癌
联合肝脏离断和门静脉结扎的两阶段肝切除术
肝再生
Liver neoplasms
Associating liver partition and portal vein ligation for staged hep- atectomy
Liver regeneration
