摘要
目的探讨立体定向靶向微创手术应用于脑胶质瘤的临床治疗效果。方法 40例脑胶质瘤患者,根据治疗方法不同分为对照组和观察组,各20例。对照组采用常规开颅肿瘤切除术进行治疗,观察组采用立体定向靶向微创手术进行治疗,观察分析两组患者的治疗效果及日常生活活动能力(ADL)评分、神经功能改善评分和2年内的存活率。结果观察组患者总有效率为95%,高于对照组的70%,差异有统计学意义(P<0.05)。观察组患者的ADL评分为(79.63±3.68)分,神经功能缺损程度评分量表(CSS)评分为(29.67±1.16)分,均优于对照组的(53.6±1.49)、(39.7±2.46)分,差异有统计学意义(P<0.05)。观察组患者2年内的存活率为80%,高于对照组的50%,差异有统计学意义(P<0.05)。结论采用立体定向靶向微创手术治疗脑胶质瘤可有效提高患者的治疗效果,改善自理能力和神经缺损程度,提高患者2年内的生存率,为胶质瘤患者的治疗提供较为科学的临床价值,值得临床信采纳。
Objective To explore the clinical curative effect of targeted stereotactic minimally invasive surgery applied in brain glioma. Methods A total of 40 brain glioma patients were divided by different treatment methods into control group and observation group, with 20 cases in each group. The control group received conventional invasive tumor resection for treatment, and the observation group received targeted stereotactic minimally invasive surgery for treatment. Observation and analysis were made on treatment effect, activities of daily living（ADL） score, nerve function improvement score and survival rate in 2 years in two groups. Results The observation group had higher total effective rate as 95% than 70% in the control group, and the difference had statistical significance（P〈0.05）. The observation group had ADL score as（79.63±3.68） points, Chinese stroke scale（CSS） score as（29.67±1.16） points, which were all better than（53.6±1.49） and（39.7±2.46） points in the control group, and the difference had statistical significance（P〈0.05）. The observation group had survival rate in 2 years as 80%, which was higher than 50% in the control group, and the difference had statistical significance（P〈0.05）. Conclusion Targeted stereotactic minimally invasive surgery can effectively increase the treatment effect of brain glioma, improve self-care ability and the degree of nerve defect, and raise survival rate of patients in 2 years. It also provide more scientific clinical value for the treatment of brain glioma, therefore it is worthy of clinical adoption.
作者
乔建华
QIAO Jian-hua(Department of Neurosurgery, Inner Mongolia Chifeng City Hospital, Chifeng 024000, Chin)
出处
《中国实用医药》
2017年第3期56-58,共3页
China Practical Medicine
关键词
立体定向微创手术
脑胶质瘤
开颅肿瘤切除术
临床效果
Targeted stereotactic minimally invasive surgery
Brain glioma
Invasive tumor resection
Clinical effect
