摘要
目的:探讨固本润肠膏对脾肾阳虚型便秘患者血管活性肠肽、P物质的影响。方法:选取脾肾阳虚型便秘患者60例,由SPSS软件制作随机码表随机分为研究组(口服固本润肠膏)和对照组(口服琥珀酸普芦卡必利),分别对两组患者治疗前后,包括生理和心理的不适、焦虑与担心以及患者对治疗的满意度进行自行评估打分,得分越高者说明生活质量越低;应用酶联免疫法检测患者血清血管活性肠肽(VIP)、P物质(SP)水平。结果:对照组便秘患者生活质量量表(PAC-QOL)得分显著高于研究组(P<0.05);对照组血清血管活性肠肽、P物质的水平均明显低于研究组(P<0.05)。结论:固本润肠膏对脾肾阳虚型便秘疗效显著.
Objective： Discuss gubenrunchang paste affects the vasoactive intestinal peptide and substance P in the spleen kidney Yang deficiency type constipation patients. Method： Select 60 patients with spleen and kidney Yang deficiency type constipation, produced by SPSS software were randomly divided into research group （ oral Gubenrunchang paste ） and the control group （ oral Prucalopride Succinate Tablets ） .And respectively on two groups of patients before and after treatment, both physical and psychological discomfort, anxiety and worry, and patients of treatment satisfaction rat- ing on its own, score the more higher shows the lower quality of life. And lastly, using the enzyme-linked immunoassay to detect the patients serum levels of vasoactive intestinal peptide （ VIP ） and substance P （ SP ）. Results ： Control con- stipation patients quality of life scale （ PAC - QOL ） significantly higher （ P 〈 0.05 ） ; and the control group serum level of vasoactive intestinal peptide and substance P were significantly lower than the research one （ P 〈 0.05 ） .Conclusion ： Curative effect of Gubenrunchang paste treatment of spleen and kidney Yang deficiency type constipation is distinct.
出处
《中医药临床杂志》
2017年第2期239-241,共3页
Clinical Journal of Traditional Chinese Medicine
关键词
固本润肠膏
脾肾阳虚型便秘
血管活性肠肽
P物质
PAC-QOL量表
Gubenrunchang paste
the spleen kidney Yang deficiency type constipation
vasoactive intestinal pep-tide
substance P
Constipation patients quality of life scale
