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脑CT血管造影及灌注成像诊断短暂性脑缺血发作的临床对照 被引量:6

Brain CT angiography and perfusion imaging in the diagnosis of clinical control of transient ischemic attack
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摘要 目的探讨脑CT血管造影(CTA)及脑CT灌注成像(CTPI)在诊断短暂性脑缺血发作(TIA)中的应用价值。方法选择2015年2月至2016年1月期间诊断为的TIA患者73例为对象,所有患者均行CTA和CTPI检查。比较两种检查方法对责任血管的显示情况,比较患侧与镜像区、不同分期患侧的CTPI参数。结果 CTA显示责任血管狭窄的57例中,CTPI显示责任血管异常的49例,阳性率85.96%;CTA显示责任血管无狭窄的16例中,CTPI显示异常的5例,阳性率31.25%,责任血管狭窄的异常阳性率高于责任血管无狭窄者,二者比较差异有统计学意义(P<0.05)。患侧的达峰时间(TTP)、局部脑血流(RCBF)和平均通过时间(MTT)参数值分别为(14.32±0.67)s、(56.48±4.33)[ml(100 g·min)]和(43.75±2.31)s,与镜像区的(10.24±0.43)s、(67.73±5.26)[ml(100 g·min)]和(35.48±3.64)s比较,患侧TTP和MTT参数值明显高于镜像区,RCBF参数值明显低于镜像区,差异具有统计学意义(P<0.01)。Ⅰ期患者的TTP、RCBF和MTT参数值分别为(12.48±0.54)s、(61.42±3.28)[ml(100 g·min)]和(39.82±2.14)s,Ⅱ期患者的TTP、RCBF和MTT参数值分别为(15.26±0.72)s、(51.44±4.73)[ml(100 g·min)]和(45.28±2.76)s,Ⅰ期TTP和MTT参数值明显低于Ⅱ期,RCBF参数值明显高于Ⅱ期,差异有统计学意义(P<0.05)。结论 CTA和CTPI均能显示TIA患者脑内病变,TTP、RCBF和MTT在TIA的鉴别诊断及临床分期中具有重要的参考价值。 Objective To explore the value of the brain CT angiography( CTA) and brain CT perfusion imaging( CTPI) in the diagnosis of transient ischemic attack( TIA). Methods During February 2015 to January 2016,a total of 73 cases of patients with TIA were performed CTA and CTPI examination. The display of the culprit blood vessels by the two methods were compared,and CTPI parameters were observed. Results CTA showed 57 cases of culprit vascular stenosis,CTPI show 49 cases of abnormal blood vessels( 85. 96 %); CTA showed culprit vessels without narrow in 16 cases,CTPI showed abnormal in 5 cases,the positive rate was 31. 25 %. There was significant statistical difference(P〈0.05). Side of TTP,RCBF and determined by MTT parameter values were( 14. 32 ± 0. 67) s,( 56. 48 ± 4. 33) [ml /( 100 g·min) ] and( 43. 75 ± 2. 31) respectively,and those in the mirror image area were( 10. 24 ± 0. 43) s,( 67. 73 ± 5. 26) [ml/( 100 g·min) ]and( 35. 48 ±3. 64) s. They had significant statistical difference( P〈0.01). The TTP,RCBF and MTT parameter values in patients with stage I were( 12. 48± 0. 54) s,( 61. 42 ± 3. 28) [ml /( 100 g·min) ]and( 39. 82 ± 2. 14) s respectively,and those in patients with stage Ⅱ were( 15. 26 ± 0. 72)s,( 51. 44 ± 4. 73) [ml /( 100 g·min) ]and( 45. 28 ± 2. 76) s. They had significant statistical difference( P〈0.05). Conclusion The CTA and CTPI can show brain lesions in TIA patients,TTP,RCBF and MTT have important reference value in the differential diagnosis and clinical staging of TIA.
作者 王靖红
出处 《临床和实验医学杂志》 2017年第6期607-610,共4页 Journal of Clinical and Experimental Medicine
关键词 短暂性脑缺血发作 电子计算机体层扫描 血管造影 灌注成像 Transient ischemic attack Electronic computer tomography CTA CTPI
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