摘要
目的了解2004-2014年云南省西双版纳地区真菌性角膜炎的人口学特征及病因。设计回顾性病例系列。研究对象2004年7月-2014年7月西双版纳州人民医院眼科599例真菌性角膜炎患者。方法回顾分析患者的人口学特征、发病诱因、病原学特征及既往诊疗情况等。主要指标人口学特征、病因及致病菌。结果男女患病比为3:1,年龄35~65岁者占47.5%,农民为主(63.4%),雨季为高发季节(85.4%)。发病诱因中植物性外伤78.4%。未确诊前治疗使用糖皮质激素者占32.5%。致病菌中镰刀菌占37.8%、烟曲霉菌占32.7%。结论男性中壮年农民雨季植物性外伤是西双版纳热带地区真菌性角膜炎主要患病危险因素。
Objective To analyze clinical features and pathogen of fungal keratitis in Xishuangbanna Autonomous Prefecture, Yunnan Province in 2004-2014. Design Retrospective case series. Participants 599 cases of fungal keratitis patients confirmed by Xishuangbanna Prefecture People's Hospital. Methods All cases were retrospectively reviewed for emographic characteristics, predispos- ing factors, etiological characteristics and previous treatments. Main Outcome Measures Emographic characteristics, etiology and pathogens. Results Prevalence ratio of male and female was 3:1, with major age range from 35 to 65 (47.5%). Rural residents were 63.4%. There was a high incidence of fungal keratitis in wet season of Xishuangbanna area (85.4%). 78.4% cases were associated with plant-in- duced trauma. 32.5% patients had received glucocorticoid medication in early treatment. Fusarium (37.8%), aspergillus (32.7%) were the main pathogenic bacteria of fungal keratitis. Conclusions Young and middle-aged male farmers, plant-induced ocular trauma in rainy season are the main risk factors of fungal keratitis in Xishuangbanna area.
出处
《眼科》
CAS
CSCD
北大核心
2017年第1期49-51,共3页
Ophthalmology in China
基金
海南医学院附属医院青年培育基金项目(HYFYPY201603)