摘要
目的探讨地佐辛术毕前给药对全麻下腹腔镜手术患者苏醒期躁动和应激反应的影响。方法选取该院2015-08~2016-03收治的300例全麻下腹腔镜手术患者为研究对象,按照随机数字表法将其分为对照组(149例)和观察组(151例)。对照组手术结束前给予生理盐水,观察组手术结束前缝皮时给予地佐辛,观察两组患者的躁动评分及镇定评分量表,分析其苏醒期躁动与应激反应情况。结果观察组躁动评分为(0.38±0.10)分,低于对照组的(1.33±0.24)分,镇静评分为(2.14±0.35)分,高于对照组的(1.56±0.15)分(P<0.01)。观察组躁动缓解率为100.00%,高于对照组的61.76%(P<0.01);观察组不良反应发生率为4.63%,低于对照组的6.71%(P>0.05)。结论采用地佐辛术毕前镇痛处理方案可降低苏醒期患者躁动发生率及应激反应发生率,镇痛效果佳,安全性高,值得临床推广应用。
Objective To explore the effects of dezocine administered on restlessness and stress reactions for the patients undergoing laparoscopies under general anesthesia prior to surgeries. Methods Three hundred patients undergoing laparoscopies under general anesthesia in our hospital from August 2015 to March 2016 were selected as the research subjects,and divided into the control group（n = 149） and the observation group（n = 151） by the random number table. The patients in the control group were administered with saline before the ending of the surgery and the patients in the observation group were administered with dezocine while undergoing intradermic suture before the end of the surgery. The sedation score scales of the patients were compared between the two groups,and the corresponding restlessness and stress reactions of the patients in the two groups were analyzed. Results The scores of restlessness in the observation group（0. 38 ± 0. 10） were significantly lower than those in the control group（1. 33 ±0. 24）,and the sedation scores of the observation group（2. 14 ± 0. 35） were significantly higher than those of the control group（1. 56 ± 0. 15）（P〈0. 05）. The remission rate of restlessness in the observation group（100%） was significantly higher than that in the control group（61. 76%）（P〈0. 05）. The incidence of adverse reactions in the observation group（4. 63%） was lower than that in the control group（6. 71%）（P〉0. 05）. Conclusion Dezocine is safe and effective for restlessness and stress reaction during recovery period in the patients before laparoscopy under general anesthesia.
出处
《中国临床新医学》
2017年第2期154-157,共4页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
关键词
地佐辛
全身麻醉
躁动
应激反应
Dezocine
General anesthesia
Restlessness
Stress reaction
