摘要
目的探讨前列舒通胶囊联合坦索罗辛治疗IIIB型前列腺炎的临床疗效。方法以2015年8月—2016年8月在南阳市中心医院进行治疗的88例ⅢB型前列腺炎患者为研究对象,根据治疗方案的差别分为对照组和治疗组,每组各44例。对照组口服盐酸坦索罗辛缓释胶囊,1粒/次,1次/d。治疗组在对照组基础上口服前列舒通胶囊,3粒/次,3次/d。两组患者均连续治疗6周。观察两组的临床疗效,比较两组NIH-CPSI评分、白细胞、最大尿流率的情况。结果治疗后,对照组、治疗组总有效率分别为79.55%、95.45%,两组总有效率比较差异有统计学意义(P<0.05)。治疗后,两组疼痛不适、排尿症状、生活质量评分和NIH-CPSI评分总分均显著降低,同组治疗前后比较差异有统计学意义(P<0.05);且治疗组降低得更显著,两组比较差异有统计学意义(P<0.05)。治疗后,两组前列腺液中白细胞显著降低,最大尿流率显著升高,同组治疗前后比较差异有统计学意义(P<0.05);且治疗组这些观察指标的改善程度明显优于对照组,两组比较差异具有统计学意义(P<0.05)。结论前列舒通胶囊联合盐酸坦索罗辛缓释胶囊治疗IIIB型前列腺炎效果显著,可明显改善患者临床症状,值得临床推广应用。
Objective To investigate clinical curative effect of Qianlie Shutong Capsules combined with tamsulosin in treatment of non inflammatory prostatitis. Methods Patients（88 cases） with non inflammatory prostatitis in Nanyang City Center Hospital from August 2015 to August 2016 were randomly divided into control and treatment groups based on different treatments, and each group had 44 cases. Patients in the control group were po administered with Tamsulosin Hydrochloride Sustained Release Capsules, 1 capsule/time, once daily. Patients in the treatment group were po administered with Qianlie Shutong Capsules on the basis of the control group, three capsules/time, three times daily. Patients in two groups were treated for 3 weeks. After treatment, the clinical efficacies were evaluated, and NIH-CPSI scores, WBC, and maximum urine flow rate in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 79.55% and 95.45%, respectively, and there were differences between two groups（P〈 0.05）. After treatment, pain discomfort, voiding symptoms, quality of life, and total scores in NIH-CPSI scores in two groups were significantly decreased, and the difference was statistically significant in the same group（P〈 0.05）. And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups（P〈 0.05）. After treatment, prostate fluid WBC in two groups were significantly decreased, but maximum urine flow rates in two groups were significantly increased, and the difference was statistically significant in the same group（P〈 0.05）. And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups（P〈 0.05）. Conclusion Qianlie Shutong Capsules combined with Tamsulosin Hydrochloride Sustained Release Capsules has clinical curative effect in the treatment of non inflammatory
出处
《现代药物与临床》
CAS
2017年第2期293-295,共3页
Drugs & Clinic
