摘要
骨重建是一种有序的骨吸收一骨形成耦联过程。不同骨骼细胞所分泌的细胞因子及细胞表面膜分子参与调控骨耦联。深入认识骨耦联机制对于研究和诊断骨质疏松等代谢性骨病有重要的指导意义。本文就一些重要的细胞因子及相关膜分子调控骨耦联机制的新进展加以概述。
Bone remodeling is an ordered process of coupling of bone resorption and bone formation. Cytokines secreted by different bone cells and membrane molecules expressed by bone cells are involved in regulation of coupling of bone resorption and bone formation. To reveal the mechanism of bone coupling is of great significance in the study and diagnosis of osteoporosis and other metabolic bone diseases. In the present review, we summarize the progression of mechanisms by which cytokines and the related membrane molecules are regulating the coupling of bone resorption and bone formation.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2017年第2期156-158,共3页
Chinese Journal of Endocrinology and Metabolism
基金
国家自然科学基金（81270962）志谢中南大学中央高校基本科研业务费专项资金资助项目（2016zzts539）
关键词
骨重建
骨耦联
细胞因子
膜分子
Bone Remodeling
Bone coupling
Cytokines
membrane molecules
