摘要
目的了解中国三亚地区妊娠期糖尿病(gestational diabetes mellitus,GDM)发病率及相关因素,进而为有针对性地进行早期防治提供理论依据。方法选取2015年06月至2016年06月在三亚市妇幼保健院妇产科门诊进行产前检查的孕24~28w的孕妇4175例,均予实施75g口服葡萄糖耐量试验(oral glucose tolerance test,OGTT),采用2014年国际糖尿病与妊娠研究组(International association of diabetes and pregnancy study groups,IADPSG)制定的GDM诊断标准计算GDM的发病率。随后将OGTT(+)者设为研究组,OGTT(-)者为对照组,同时采集孕妇人口资料。其中,统计分布描述采用χ~2检验和Logistic回归分析。结果三亚地区GDM发病率约为11.52%(481/4175)。研究组年龄、OGTT时身体质量指数(body mass index,BMI)、空腹血糖(fasting plasma glucose,FPG)和甘油三酯(triglyceride,TG)明显高于对照组,差异有非常显著性统计学意义(P<0.01)。其中,年龄和OGTT时BMI与GDM的发病率呈正相关。同时,研究组既往不良妊娠史亦明显高于对照组,差异亦有非常显著性统计学意义(P<0.01)。Logistic回归分析结果显示:糖尿病家族史、年龄、OGTT时BMI、文化程度、经济条件和业余生活是导致GDM的相关因素(P<0.01或0.05)。结论中国·三亚地区GDM的发病率为11.52%。其中,糖尿病家族史、年龄、OGTT时BMI是GDM的独立高危因素,建议相关职能部门针对相关因素实施防治,以期降低GDM发病率。
Objective：Study of Sanya in gestational diabetes mellitus（GDM）prevalence and related factors,then for a targeted to provide theoretical basis for early prevention. Methods：Select from June 2015 to June 2016 in Sanya City MCH obstetrics and gynecology clinic for prenatal care of pregnant women pregnant 24 - 28 w 4175 cases. To implement the 75 g oral glucose tolerance test. The GDM was diagnosed according to IADPSG criteria in 2014. Then OGTT（＋） is set to the research group,OGTT（-）as a control. At the same time,the pregnant women′s population dates were collected. Statistical distribution to describe the chi-square test and Logistic regression analysis. Results：Prevalence of GDM in Sanya district was 11.52%（481/4175）. The research group of age,body mass index（BMI）at OGTT,fasting plasma glucose（FPG）and triglyceride（TG）is significantly higher than the control group. There are a very significant difference statistically significant（P〈0.01）. Among them,the prevalence of GDM showed positive correlation between age and BMI at OGTT. And the research group history of adverse pregnancy was also significantly higher than the control group（P〈0.01）. Logistic regression analysis showed that family diabetic history,age,BMI at OGTT,degree of education,economic condition and sparetime life in GDM are the related factors and statistical values P〈0.01 or 0.05. Conclusion：Prevalence of GDM in Sanya district was 11.52%. Among them,the family diabetic history,age,BMI at OGTT are independent risk factors for GDM. Thus relevant functional departments aim at related factors to prevention and control that in order to reduce the incidence of GDM.
出处
《中国优生与遗传杂志》
2017年第2期88-90,132,共4页
Chinese Journal of Birth Health & Heredity
