摘要
目的评价高增强征象在超声、CT及2者联合诊断甲状腺良、恶性结节中的价值。方法回顾分析经手术病理证实的144例172枚甲状腺结节超声造影和CT增强检查资料,包括97枚良性结节和75枚恶性结节,依据增强程度均分为等低增强和高增强,统计超声高增强、CT高增强、超声和CT均高增强在甲状腺良性结节与恶性结节、腺瘤样病变与结节性甲状腺肿中的分布,并采用χ2检验进行统计学分析。结果172枚甲状腺结节中,超声高增强、CT高增强、超声和CT均高增强在良性结节和恶性结节中分别占53.6%(52/97)和20.0%(15/75)(χ2=20.090,P〈0.05)、34.0%(33/97)和4.0%(3/75)(χ2=23.033,P〈0.05)、31.0%(30/97)和0%(0/75)(χ2=28.096,P〈0.05),3者诊断良性结节的敏感度和特异度分别为53.6%(52/97)和80.0%(60/75)、34.0%(33/97)和96%(72/75)、30.9%(30/97)和100%(75/75);超声高增强、CT高增强、超声和CT均高增强在腺瘤样病变和结节性甲状腺肿中所占比例分别为96.9%(31/32)和32.3%(21/65)(χ2=35.946,P〈0.05)、65.6%(21/32)和18.5%(12/65)(χ2=21.250,P〈0.05)、65.6%(21/32)和13.8%(9/65)(χ2=26.912,P〈0.05),3者诊断腺瘤样病变的敏感度和特异度分别为96.9%(31/32)和67.7%(44/65)、65.6%(21/32)和81.5%(53/65)、65.6%(21/32)和87.2%(56/65)。结论超声高增强与CT高增强对甲状腺良性结节的诊断均具有重要价值,尤其是腺瘤样结节,超声高增强具有更高的敏感度,CT高增强具有更高的特异度,2者联合可进一步提高诊断的特异度,从而减少不必要的手术创伤。
ObjectiveTo investigate the diagnostic value of hyperenhancement sign on ultrasound, CT and their combination in diagnosis of thyroid benign and malignant nodules.MethodsThe contrast-enhanced ultrasound and enhanced CT datas of 172 thyroid nodules in 144 cases confirmed by operation and pathology were retrospectively analyzed, including 97 benign nodules and 75 malignant nodules. According to the degree of enhancement, these nodules were divided into iso- or low-enhancement and hyperenhancement. The distributions of ultrasound hyperenhancement, CT hyperenhancement and both of them in thyroid benign and malignant nodules, adenomatoid lesions and nodular goiters were analyzed, followed by χ2 test for statistical analysis.ResultsIn 172 thyroid nodules, the proportions of ultrasound hyperenhancement, CT hyperenhancement and both of them in thyroid benign and malignant nodules were 53.6% (52/97) and 20.0% (15/75) (χ2=20.090, P〈0.05) , 34.0% (33/97) and 4.0% (3/75) (χ2=23.033, P〈0.05) , 31.0% (30/97) and 0% (0/75) (χ2=28.096, P〈0.05) , respectively. Their sensitivity and specificity of diagnosing benign nodules were 53.6% (52/97) and 80.0% (60/75) , 34.0% (33/97) and 96% (72/75) , 30.9% (30/97) and 100% (75/75) , respectively. The proportions of ultrasound hyperenhancement, CT hyperenhancement and both of them in adenomatoid lesions and nodular goiters were 96.9% (31/32) and 32.3% (21/65) (χ2=35.946, P〈0.05) , 65.6% (21/32) and 18.5% (12/65) (χ2=21.250, P〈0.05) , 65.6% (21/32) and 13.8% (9/65) (χ2=26.912, P〈0.05) . Their sensitivity and specificity of diagnosing adenomatoid lesions were 96.9% (31/32) and 67.7% (44/65) , 65.6% (21/32) and 81.5% (53/65) , 65.6% (21/32) and 87.2% (56/65) .ConclusionsUltrasound hyperenhancement, CT hyperenhancement for diagnosing thyroid benign nodules are of significant value. Especially for adenomatoid nodules, ultrasound hyperenhancement has a higher
出处
《中华内分泌外科杂志》
CAS
2017年第1期15-19,共5页
Chinese Journal of Endocrine Surgery
基金
浙江省公益技术应用研究项目(2017C33180)
2015年杭州市卫生科技计划项目(2015A21)
2015年浙江省医药卫生一般研究计划(2015KYB293)
2013杭州市重大科技创新专项项目(20131813A08)
关键词
甲状腺结节
超声造影
体层摄影术
X线计算机
Thyroid nodule
Contrast-enhanced ultrasound
Tomography
X-ray computed