摘要
目的探讨无创呼吸机在慢性阻塞性肺疾病急性加重期(AECOPD)并发Ⅱ型呼吸衰竭患者中的临床应用效果。方法 92例AECOPD并发Ⅱ型呼吸衰竭患者,随机分为对照组和观察组,各46例。对照组采用常规抗感染药物和氧气吸入治疗,观察组在对照组治疗基础上同时辅助无创呼吸机治疗。观察两组患者的治疗效果。结果观察组治疗后动脉血氧分压(PaO_2)、动脉血二氧化碳分压(PaCO_2)、动脉血氧饱和度(SaO_2)均明显优于对照组,差异均有统计学意义(P<0.01或P<0.05)。结论采用抗感染药物的同时辅助无创呼吸机治疗AECOPD并发Ⅱ型呼吸衰竭,可显著改善此类患者血气分析指标,减少患者的痛苦,值得临床推广应用。
Objective To investigate clinical application effect by non-invasive ventilator in patients of acute exacerbation of chronic obstructive pulmonary disease（AECOPD） complicated with type Ⅱ respiratory failure. Methods A total of 92 patients of AECOPD complicated with type Ⅱ respiratory failure were randomly divided into control group and observation group, with 46 cases in each group. The control group received conventional anti-infective drug and oxygen inhalation for treatment, and the observation group received additional non-invasive ventilator to treatment in the control group. Curative effects of the two groups were observed. Results The observation group had all better arterial partial pressure of oxygen（PaO2）, arterial partial pressure of carbon dioxide（PaCO2）, and arterial oxygen saturation（SaO2） after treatment than the control group, and their differences all had statistical significance（P〈0.01 or P〈0.05）. Conclusion Implement of additional non-invasive ventilator to anti-infective drug can remarkably improve blood gas indexes and reduce pain in patients of AECOPD complicated with type Ⅱ respiratory failure. This method is worthy of clinical promotion and application.
出处
《中国实用医药》
2016年第3期21-22,共2页
China Practical Medicine
关键词
无创呼吸机
慢性阻塞性肺疾病
急性加重期
呼吸衰竭
Non-invasive ventilator
Chronic obstructive pulmonary disease
Acute exacerbation
Respiratory failure
