摘要
目的 探讨动脉瘤性蛛网膜下腔出血（a SAH）患者继发性癫痫的危险因素。方法 对2009年3月-2015年5月在我院神经外科行显微手术夹闭的162例a SAH患者的临床资料进行回顾性分析,将继发性癫痫分为早期癫痫和晚期癫痫,分析a SAH患者继发早、晚期癫痫的危险因素,包括年龄、性别、原发性高血压病史、起病时意识障碍持续时间、入院时格拉斯哥昏迷评分（GCS）、Fisher分型、责任动脉瘤的部位、脑血管痉挛、脑积水、动脉瘤再破裂以及格拉斯哥预后分级（GOS）。结果 162例a SAH患者中,早期癫痫14例,晚期癫痫18例。原发性高血压病史为发生早期癫痫的危险因素（P〈0.05）;脑积水和动脉瘤再破裂为发生晚期癫痫的危险因素（P〈0.05）。结论原发性高血压病史可能是a SAH继发早期癫痫的危险因素,而脑积水和动脉瘤再破裂则可能是继发晚期癫痫的危险因素。
Objective To investigate the risk factors for secondary epilepsy after aneurysmal subarachnoid hemorrhage （aSAH）. Methods From March 2009 to May 2015,the clinical data of 162 patients with aSAH treated by microsurgical clipping at the Department of Neurosurgery were analyzed retrospectively. The seizures after aSAH were divided into early epilepsy and late epilepsy. The risk factors for early and late seizures in patients with aSAH were analyzed,including age, sex, history of hypertension, duration of disturbance of consciousness at the onset, Glasgow Coma Scale （GCS） on admission, Fisher grade, locations of guilty aneurysms, cerebral vasospasm, hydrocephalus, Aneurysm rupture and Glasgow Outcome Scale （GOS）. Results In 162 patients with aSAH, 14 cases of early epilepsy,and 18 cases of late epilepsy. The history of hypertension might associated with the occurrence of early epilepsy （P〈0.05）. Hydrocephalus and aneurysm rupture might associate with the occurrence of late epilepsy（P〈0.05）. Conclusion The history of hypertension may be the risk factor for secondary early epilepsy after aSAH, while the hydrocephalus and aneurysm rupture may be the risk factor for secondary late epilepsy after aSAH.
出处
《中国现代医生》
2016年第36期14-17,共4页
China Modern Doctor
基金
浙江省中医药科学研究基金(2014ZSZX12)
