摘要
目的探究抗生素合理用药管理在颅脑手术中的应用。方法选取了2014年3月—2015年12月于该院进行颅脑手术的234例患者,按照抗生素合理使用原则给予相应种类、剂量的抗生素作为观察组,另选取2014年3月之前,未对抗生素的合理用药进行规范管理的234例颅脑手术患者作为对照组。根据颅脑手术术后颅内感染判断标准,确定对照组及观察组的颅内感染人数,比较两者差异有统计学意义。结果对合理使用抗生素进行规范化管理的观察组的234例患者,其中有13例患者在颅脑手术后出现颅内感染,颅内感染发生率为5.56%;未对合理使用抗生素进行规范化管理的234例患者,其中89例患者在颅脑手术后出现颅内感染,颅内感染发生率为38.03%,对照组与观察组进行统计学比较,两者差异有统计学意义(P<0.05)。结论对颅脑手术患者进行抗生素合理用药管理,能够降低患者术后颅内感染的发生率,利于患者康复。
Objective To study the application of rational medication management of antibiotics in the craniocerebral operation. Methods 234 cases of patients with craniocerebral operation in our hospital from March 2014 to December 2015 were selected as the observation group with rational management of antibiotics, and 234 cases of patients with craniocerebral operation without rational management of antibiotics before March 2014 were selected as the control group, and intracranial infection number of the two groups was defined according to the intracranial infection criterions after the craniocerebral operation. Results There were obvious differences in the intracranial infection number and incidence rate of intracranial infection between the observation group and the control group（13 cases, 5.56% vs 89 cases, 38.03%）,（P〈0.05）. Conclusion The rational medication management of antibiotics for patients with craniocerebral operation can reduce the incidence rate of intracranial infection after operation, which is conducive to rehabilitation of patients.
出处
《中国卫生产业》
2017年第2期123-124,共2页
China Health Industry
关键词
抗生素
合理使用
颅脑手术
颅内感染率
Antibiotics
Rational use
Craniocerebral operation
Intracranial infection rate
