摘要
目的探讨颅脑手术患者脑脊液降钙素原(PCT)水平与其创伤程度的关系。方法选择2013年1月至2014年1月期间于我院进行颅脑手术治疗的患者120例,按手术原因分为高血压脑出血组58例和颅脑外伤组62例,另选取30例健康查体者作为对照组。统计分析3组脑脊液PCT水平和APACHEⅡ评分,比较高血压脑出血组和颅脑外伤组术后不同时间的脑脊液PCT水平和APACHEⅡ评分,分析其脑脊液PCT水平与其APACHEⅡ评分的关系。结果脑外伤组脑脊液降钙素原水平和APACHEⅡ评分均较高血压脑出血组升高,且高血压脑出血组和颅脑外伤组脑脊液PCT水平和APACHEⅡ评分亦均较对照组升高,差异有统计学意义(P<0.05)。颅脑外伤组术后不同时间的平均脑脊液PCT水平和APACHEⅡ评分均较高血压脑出血组升高,差异有统计学意义(P<0.05)。高血压脑出血组平均脑脊液PCT水平于术后48h达到峰值,为(214.52±74.58)pg/mL,颅脑外伤组患者36h达到峰值,为(416.27±76.82)pg/mL,两组达峰时间和峰值比较差异有统计学意义(P<0.05)。Pearson相关性分析结果显示,高血压组患者脑脊液降钙素原水平与APACHEⅡ评分无明显相关性(r=0.242,P>0.05)。颅脑外伤组患者脑脊液降钙素原水平和SAPACHEⅡ评分呈正相关(r=0.743,P<0.05)。结论颅脑外伤手术患者脑脊液降钙素原水平明显升高,且其脑脊液降钙素原水平与其APACHEⅡ评分相关,颅脑手术患者脑脊液降钙素原水平可在一定程度上反映其创伤程度。
Objective To investigate the ncurolymph procalcitonin（PCT）level in patients treated with operations on cranium and brain and the relationship with trauma degree.Methods A total of 120 patients treated with operations on cranium and brain in our hospital from January 2013 to January 2014 were divided into hypertension cerebral hemorrhage group（n=58）and traumatic brain injury group（n=62）according to the surgical reasons.Thirty healthy persons who had physical examination in our hospital were selected as control group.Ncurolymph PCT levels and APACHE Ⅱ score of three groups were statistically analyzed,postoperative ncurolymph PCT levels and APACHE Ⅱ score of hypertension cerebral hemorrhage group and traumatic brain injury group were compared,and relationship between ncurolymph PCT levels and APACHE Ⅱscore were analyzed.Results Ncurolymph PCT levels and APACHE Ⅱ score of brain trauma group cerebrospinal were higher than that of the hypertension cerebral hemorrhage group.And ncurolymph PCT levels and APACHE Ⅱ score of hypertension cerebral hemorrhage group and traumatic brain injury group were higher than that of the control group.The difference was statistically significant（P0.05）.Average postoperative ncurolymph PCT level of traumatic brain injury group were higher than that of the hypertension cerebral hemorrhage group,and the difference was statistically significant（P0.05）.Ncurolymph PCT level of hypertension cerebral hemorrhage group had reached its average peak level（214.52±74.58pg/mL）48hours postoperative.Ncurolymph PCT level of traumatic brain injury group reached its average peak level（416.27±76.82pg/mL）36hours postoperative,and the difference between the two groups had statistical significance（P0.05）.Pearson correlation analysis results showed that Ncurolymph PCT levels and APACHE Ⅱ score of hypertension group had no significant correlation（r=0.242,P0.05）,while Ncurolymph PCT levels and APACHE Ⅱ score of traumatic brain injury group were positively correla
出处
《青岛医药卫生》
2017年第1期1-5,共5页
Qingdao Medical Journal
关键词
颅脑手术
脑脊液
降钙素原
创伤程度
关系
Craniocerebral surgery
Ncurolymph
Procalcitonin
Trauma degree
Relationship
