摘要
目的探索影响妊娠早期抑郁的相关因素。方法采用爱丁堡产后抑郁量表(Edinburgh postpartum depression scale,EPDS)和中文版知觉心理压力量表(Chinese perceived stress scale,CPSS),于2013年11月20日-2014年9月22日在江西省乐平市妇幼保健院产前门诊招募孕周<20周的孕妇648名进行调查,使用Logistic多因素回归分析产前抑郁的相关因素。结果本研究抑郁得分分布为8.0(P_(25))、11.0(P_(50))、13.8(P_(75)),总检出率为20.4%。多因素分析发现,心理压力达到健康危险性压力状态(Health risk stress,HRS)的妇女患有产前抑郁的相对危险度显著高于心理压力正常的妇女(aOR=3.76,95%CI:2.08~6.80,P<0.001),孕前月经规律的妇女患有产前抑郁的风险显著低于孕前月经不规律的妇女(aOR=0.55,95%CI:0.30~0.98,P=0.044)。结论孕期高心理压力与孕前月经失调可能是引起产前抑郁的相关危险因素。
Objective To explore the related factors of depression during early pregnancy.Methods A total of 648 pregnant women with gestational week20 weeks were selected from Leping Maternal and Child Health Care Hospital from November 20 th,2013 to Sptember22 nd,2014,then they were surveyed by Edinburgh Postpartum Depression Scale（ EPDS） and Chinese Perceived Stress Scale（ CPSS）.Logistic regression analysis was applied to analyze the related factors of antepartum depression.Results The distribution of antepartum depression score was 8.0（ 25 percentile）,11.0（ 50 percentile） and 13.8（ 75 percentile）,respectively.The total detection rate of antepartum depression was 20.4%.Multivariate logistic analysis showed that the relative risk of antepartum depression in pregnant women with high level of health risk stress（ HRS） was statistically significantly higher than that in pregnant women with normal psychological stress（ aOR =3.76,95% CI： 2.08- 6.80,P〈0.001）,the relative risk of antepartum depression in pregnant women with regular menstruation before pregnancy was statistically significantly lower than that in pregnant women with irregular menstruation before pregnancy（ aOR = 0.55,95%CI： 0.30-0.98,P = 0.044）.Conclusion Maternal high psychological stress during pregnancy and menstrual disorder before pregnancy are possible risk factors associated with antepartum depression during early pregnancy.
出处
《中国妇幼保健》
CAS
2017年第3期451-454,共4页
Maternal and Child Health Care of China
基金
上海市第四轮公共卫生三年行动计划重点学科建设资助(15GWZK0402)
UBS Optimus Foundation资助
