摘要
目的应用脉冲多普勒和组织多普勒两种方法测量重度子痫前期患者右室心肌做功指数(Tei指数),探讨Tei指数评价右心功能的可行性。方法回顾性分析2013年10月至2015年9月在绍兴市妇幼保健院住院分娩的135例孕妇,其中重度子痫前期患者(观察组)55例和血压正常孕妇(对照组)80例。测定两组孕妇的一般临床资料、右室射血分数(RVEF)、三尖瓣瓣口舒张早期E波峰值流速与舒张晚期A波峰值流速之比(E/A)等。采用脉冲多普勒法(Tei1)和组织多普勒法(Tei2)测量右室Tei指数,并将两组孕妇的Tei指数合并后,采用Pearson相关分析比较两种Tei测量方法的相关性。结果观察组孕妇心脏收缩压和舒张压较对照组均有显著升高[(170±7)mm Hg vs.(108±12)mm Hg、(117±6)mm Hg vs.(72±8)mm Hg,t=37.390、36.803,P均<0.05];而RVEF与E/A比较差异均无统计学意义(P均>0.05)。观察组右室Tei1和Tei2指数较对照组均显著增高[(0.58±0.11)vs.(0.35±0.12)、(0.60±0.12)vs.(0.38±0.11),t=11.809、11.256,P均<0.05]。同时,将对照组和观察组合并后,Tei1与Tei2指数比较差异无统计学意义[(0.45±0.16)vs.(0.47±0.16),t=1.212,P=0.227],且两指数呈正相关(r=0.908,P<0.001)。结论Tei指数可以准确反映重度子痫前期患者右心整体功能;运用组织多普勒法和脉冲多普勒法测量右室Tei指数比较无明显差异,并具有高度的相关性。
Objective To investigate the fight ventricular myocardial performance index (Tei index) in patients with severe preeclampsia by applying pulse Doppler and tissue Doppler, and to explore the feasibility of Tei index in the evaluation of right ventricular funetion. Methods One hundred and thirty-five parturients admitted to Shaoxing Women & Children's Hospital from October 2013 to September 2015 were enrolled in this retrospective study. They were divided into the observation group (55 eases with severe preeclampsia) and control group (80 cases with normotension). These two groups were analyzed with the general clinieal data, right ventricular ejection fraetion (RVEF), the ratio of trieuspid valve diastolie early E wave peak velocity and diastolic late A wave peak velocity (E /A), etc. In addition, the pulse Doppler (Tei1) and tissue Doppler methods (Tei2) measured the right ventricular Tei index for all parturients. The method of Pearson correlation analysis investigated the correlation between two Tei index measurements, after the combination of Tei indexes in two group parturients. Results The systolic and diastolic blood pressures in the observation group were significantly higher than those in the control group [(170 ± 7) mmHg vs. (108 ± 12) mmHg, (117 ± 6) mmHg vs. (72 ±8) mmHg; t = 37.390, 36.803; all P 〈 0.05]. There were no statistically significant differences between the two groups in RVEF and E/A (all P〉 0.05). The right ventricular Tei1 index and Tei: index in the observation group were significantly higher than those in the control group [(0.58 ± 0.11) vs. (0.35 ± 0.12), (0.60 ± 0.12) vs. (0.38 ± 0.11); t = 11.809, 11.256; all P〈 0.05]. After the combination of control and observation groups, there was no statistically significant difference between Tei1 index and Tei2 index [(0.45 ±0.16) vs. (0.47 ± 0.16), t = 1.212, P=0.227], and these two indices were positively correlated (r = 0.908, P〈 0.001). Conc
作者
寿列军
解左平
谭乳燕
谢乐燕
袁华
金社红
周佳梅
汪惠琴
李红梅
Shou Liejun Xie Zuoping Tan Ruyan Xie Leyan Yuan Hua Jin Shehong Zhou Jiamei Wang Huiqin Li Hongmei(Department of Ultrasound Department of Obstetrics, Shaoxing Women & Children's Hospital, Shaoxing 312000, China)
出处
《中华危重症医学杂志(电子版)》
CAS
2016年第6期384-388,共5页
Chinese Journal of Critical Care Medicine:Electronic Edition
基金
浙江省公益性技术应用研究计划项目(2015C33296)
绍兴市公益性技术应用研究计划项目(2014B70060)
关键词
超声检查
多普勒
脉冲
心室功能
右
子痫
组织多普勒
TEI指数
Ultrasonography, Doppler, pulsed
Ventricular function, right
Eclampsia
Tissue Doppler
Tei index