摘要
目的：通过对我院2型糖尿病患者的临床资料进行回顾性分析，探讨2型糖尿病患者空腹胰岛素水平和糖基化血红蛋白与肥胖的相关性。方法：选择我院2015年6月-2016年6月收治的2型糖尿病患者60例，根据身体质量指数≥25kg／m2（肥胖）的标准进行分组，肥胖组30例，对照组30例，比较两组患者空腹糖基化血红蛋白、空腹胰岛素水平、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、血甘油三脂、血总胆固醇。结果：（1）与对照组相比，肥胖组低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、血甘油三脂、血总胆固醇、血清空腹胰岛素、空腹糖基化血红蛋白水平明显更高，数据比较差异具有统计学意义，P〈0．05。（2）空腹糖基化血红蛋白、空腹胰岛素水平与身体质量指数呈正相关的关系。结论：2型糖尿病患者空腹胰岛素水平、糖基化血红蛋白与肥胖密切相关。
Objective： To retrospectively analyze clinical data of patients with type 2 diabetes and explore the correlation of the fasting insulin levels and glycosylation hemoglobin in type 2 diabetes with obesity. Methods： 60 patients with type 2 diabetes from June 2015 -June 2016 in our hospital were selected and divided into two group： obese group and control, then compared glycosyla- tion hemoglobin, fasting insulin level, low density lipoprotein cholesterol, high-density lipoprotein cholesterol, blood triglycerides and blood total cholesterol of the two groups. Results： （1） Compared with control, low density lipoprotein cholesterol, high-density lipoprotein cholesterol, blood triglycerides, fasting insulin, fasting total cholesterol, blood plasma glycosylation of obesity group were significantly higher, the differences had statistically significance, P〈0.05. （2） The fasting hemoglobin glycosylation and insulin level were positively correlated with body mass index （bmi） . Conclusion： The fasting insulin levels and hemoglobin glycosylation in type 2 diabetes were closely related to obesity.
出处
《医学检验与临床》
2016年第9期17-18,8,共3页
Medical Laboratory Science and Clinics
