摘要
目的研究恩替卡韦治疗慢性乙型肝炎的用药效果。方法将我院2015年1-6月慢性乙型肝炎患者40例随机分两组。拉米夫定组采用拉米夫定进行治疗,恩替卡韦组采用恩替卡韦进行治疗。比较两组患者慢性乙型肝炎治疗总有效率;用药过程不良反应发生率;干预前和干预后患者肝功能的差异。结果恩替卡韦组患者慢性乙型肝炎治疗总有效率高于拉米夫定组,P<0.05;两组患者用药过程不良反应发生率对比,差异无统计学意义,P>0.05;干预前两组肝功能比较,差异无统计学意义,P>0.05;干预后恩替卡韦组肝功能改善幅度更大,P<0.05。结论恩替卡韦治疗慢性乙型肝炎的用药效果确切,可有效改善患者肝功能,改善患者病情,且无明显副作用,安全可靠,值得推广。
Objective To study the effect of entecavir in treatment of chronic hepatitis B drug effect. Methods 40 patients with chronic hepatitis B in our hospital from January to June 2015 were randomly divided into two groups. Lamivudine group using lamivudine treatment, entecavir group were treated with entecavir. two groups of patients with chronic hepatitis B treatment total effective rate of adverse drug reactions; intervention before and after intervention in patients with liver function differences were compared. Results The total effective rate is higher than the treatment group of lamivudine entecavir in patients with chronic hepatitis B, P〈0.05;adverse reactions of two groups of patients after treatment process there was no significant difference, P〉0.05; two groups before the intervention of liver function showed no significant difference, P〉0.05; after the intervention of entecavir group and liver function more improvement, P〈0.05. Conclusion Entecavir treatment of chronic hepatitis B treatment effect, can effectively improve the liver function of patients, improve the patient＇s condition, and no obvious side effects, safe and reliable.
出处
《中国继续医学教育》
2017年第2期157-158,共2页
China Continuing Medical Education
