摘要
本文对四逆散治疗抑郁症的研究进行总结,分四逆散治疗抑郁症的效应及机制研究两部分进行综述。目前的临床及动物实验研究结果均提示四逆散是一种有效、安全的抗抑郁方剂。四逆散可通过多靶点发挥抗抑郁作用,但其机制研究并不深入,且切入点多限于现代医学中公认的与抑郁症发病机制密切相关的生物学指标。对已发现的有效靶点进行深入研究,并从中医理论出发,多角度对四逆散的抗抑郁机制进行研究,是四逆散抗抑郁机制研究取得更多成果的有效途径。
This paper summarizes the research of Sini powder on the antidepressant effect and mechanism. A lot of evidence has proved that Sini powder was an effective and safe antidepressant prescription. It has been proved that Sini powder played antidepressant efficiency by multiple targets. But the research on the mechanism was not enough deeply studied, and limited to the biological factors that has been widely recognized as related with depression pathogenesis. Further mechanism research should base on the target that has been known, and the research should study from the TCM theory and multi-angle. Only by this way can have breakthrough in the study of Sini powder＇ s antidepressant mechanism.
出处
《环球中医药》
CAS
2017年第1期110-113,共4页
Global Traditional Chinese Medicine
基金
国家重点基础研究发展计划(973计划)(2011CB505106)
关键词
四逆散
抑郁症
疗效
机制
Sini powder
Depression
Therapeutic effect
Mechanism
