摘要
目的通过对社区60岁以上老人的认知功能损害(MCI)和简易精神状态等流行病调查,筛查出老人认知功能损害和早期阿尔茨海默病(AD)人群。方法选择本社区常驻户口60岁以上2000例,随机抽取400例老人,使用自编的老年一般情况调查表、蒙特利尔认知评估量表(CMOCA)、简易精神状态检查表(MMSE)、体检和必要的辅助检查,筛查MCI和AD在普通人群中的发生率和危险因素。结果 400例60岁以上老人中,完成首次检查,资料齐全的345例,男:女为110:235,其中男性与女性AD发生率为23.6%、58.96%,AD发生率男比女分别为19.09%、28.16%,危险因素分析发现年龄、文化程度、性别和有无老伴是MCI和AD的四大易患因子,其中60~69岁、70~79岁及80岁以上三个年龄组MCI发生率分别为35.85%、52.94%、67.74%,AD发生率分别为16.51%、39.22%、45.16%,显示随年龄增长,发生率显著增长;文化程度分析发现文盲、小学与中学以上文化MCI发生率分别是65.48%、45.78%、17.42%,AD发生率分别为60.71%、33.73%、5.8%;调查时有老伴与无老伴AD发生率分别为24.08%、39.13%,MCI发生率分别为32.78%、54.35%。结论社区60岁以上老人MCI和AD的发生率较高,高龄、女性、文盲和无老伴是MCI和AD的高发因素。
Objective To screen elderly mild cognitive impairment（MCI） and early Alzheimer＇s disease （AD）population through an epidemiological survey on the cognitive function impairment and the mini mental status of the elderly over 60 years old. Methods We selected the community permanent residence of more than 60 years of age in 2000 elderly, and randomly selected 400 elderly. Screen MCI and AD in the general population incidence and risk factors by using elderly general situation question- naire, montreal cognitive assessment scale（ MOCA）, Mini Mental State Examination （MMSE）, physical examination and necessary examination. Results There were 345 people with complete data who complete the first inspecting among 400 people over the age 60. The ratio of male to female was 110,235. Among them,the incidence of male and female AD was 23. 6% ,58. 96% ,and the in- cidence rate of AD was 19. 09% ,28. 16%. Risk factor analysisfind that age, educational level, gender, and whether or not the wife were the four major risk factors for AD and MCI. MCI incidence rates was 35.85% ,52. 94% ：67. 74% respectively in 60-69 years old,70-79 years old and 80 years of age group. AD incidence was 16. 51% ,39.22% ,45.16%. It showed that the incidence rate was significantly increased with age. The degree of cultural analysis find that the MCI incidence was 65.48% ,45. 78%, 17.42% respectively in illiteracy, primary school and middle school culture. AD incidence was 60. 71%, 33.73% ,5.8%. AD incidence was 24. 08% ,39. 13% respectively in have his wife group and no wife group. MCI incidence was 32. 78% ,54. 35%. Conclusion MCI and AD incidence is higher in community over 60 years old. The elderly,women, illiteracy and no wife are the risk factors of MCI and AD.
作者
谭友果
蔡端芳
甘枝勤
杨秀英
刘波
刘成文
Tan Youguo Cai Duanfang Can Zhiqin et al(The Fifth People＇s Hospital of Zigong, Zigong, Sichnan 643020, Chin)
出处
《四川医学》
CAS
2017年第1期25-28,共4页
Sichuan Medical Journal
基金
2012年自贡市重点科技计划项目(编号:2012506)
