摘要
目的探讨高频振荡通气(HFOV)治疗新生儿呼吸衰竭的疗效及安全性。方法观察31例应用HFOV患儿治疗前后氧合通气指标、呼吸机参数的变化及临床疗效。结果与治疗前相比,HFOV治疗后6h患者PaCO_2迅速下降,差异有统计学意义(P<0.05)[(70.75±16.78)mm Hg vs.(48.25±8.55)mm Hg];12h的PaO_2明显上升,差异有统计学意义(P<0.05)[(41.65±11.25)mm Hg vs.(60.15±16.32)mm Hg;吸入氧浓度(Fi O2)、血氧合指数(OI)随时间降低。治愈24例,出现颅内出血等并发症5例。结论 HFOV是治疗新生儿呼吸衰竭的安全有效的方法。
Objective To investigate the efficacy and safety of high frequency oscillatory ventilation（HFOV）in the treat- ment of neonatal respiratory failure. Methods Before and after HFOV treatment,the changes of the parameters of oxygen,the pa- rameters of the ventilator and the clinical curative effect of 31 cases of sick newborn were observed. Results Compared with before treatment, PaCO2 after 6h treatment in patients with HFOV decreased rapidly, and the difference was statistically significant（ P 〈 0.05 ） [ （70. 75± 16. 78 ）mmHg vs. （48.25 ± 8.55 ）mmHg ]. PaO2 in 12h significantly increased, and the difference was statisti- cally significant（ P 〈 0. 05 ） [ （41.65± 11.25 ） mmHg vs. （ 60. 15±16. 32） mmHg. The oxygen concentration （ FiO2 ） of the blood oxygenation index（OI） decreased with time. There were 24 cases cured,5 cases of complications such as intracranial hemorrhage. Conclusion HFOV is a safe and effective method in the treatment of neonatal respiratory failure.
作者
彭好
袁涛
夏长明
王春艳
Peng Hao Yuan Tao Xia Changming et al.(Central Hospital of Suining, Suining, Sichuan 629000, Chin)
出处
《四川医学》
CAS
2017年第1期7-9,共3页
Sichuan Medical Journal
基金
四川省科技厅应用基础计划(编号:2015JY0136)
关键词
高频振荡通气
呼吸衰竭
新生儿
high frequency oscillatory ventilation
respiratory failure
newborn
