摘要
目的：探讨全肺切除术治疗非小细胞肺癌患者的近期疗效、远期疗效及其影响因素。方法回顾性分析因非小细胞肺癌行全肺切除术患者64例的临床及随访资料。结果术后30 d 病死率为7．8％（5／64），术后并发症发生率为29．7％（19／64），5年生存率为19．0％；分期为Ⅲ期（P ＝0．030）、肿瘤位于右肺是预后差的独立预测因素（P ＝0．010）；远期生存率与组织学类型及是否为根治性切除无关（P ＝0．125、0.587）。结论全肺切除术用于非小细胞肺癌可取得尚为满意的近期及远期疗效，TNM分期为Ⅲ期或肿瘤位于右肺的非小细胞肺癌行全肺切除术需慎重。
Objective To assess the mortality,complications and major morbidity of pneumonectomy for non -small cell lung cancer（NSCLC）and to establish the importance of various prognostic factors.Methods The data of 64 consecutive patients who underwent pneumonectomy for NSCLC were retrospectively reviewed.Results The 30 -day mortality rate was 7.8%（5 /64）.Complications developed in 29.7%（1 9 /64）and overall 5 -year survival was 1 9.0%.Pathological stage Ⅲ（P =0.030）and right pneumonectomy（P =0.01 0）were independent risk factors of an adverse outcome.Survival was not significantly influenced by histological types （P =0.1 25）or curability （P =0.587）.Conclusion Pneumonectomy is associated with acceptable overall morbidity and mortality.However,the patients with pathological stage Ⅲ or right pneumonectomy require special consideration.Pneumonectomy should be performed only in selected patients.
作者
魏志平
黄海涛
姚俊
胡哲
Wei Zhiping Huang Haitao Yao Jun Hu Zhe(Department of Surgical Oncology , Taizhou Oncologic Hospital, Taizhou , Zhejiang 317502, China)
出处
《中国基层医药》
CAS
2017年第1期5-8,J0001,共5页
Chinese Journal of Primary Medicine and Pharmacy
基金
浙江省台州市科技计划项目（2014A33149）
关键词
肺切除术
癌
非小细胞肺
存活率
Pneumonectomy
Carcinoma,non -small -cell lung
Survival rate
