期刊文献+

外周血血小板/淋巴细胞比值在非小细胞肺癌诊断中的价值 被引量:12

下载PDF
导出
摘要 目的探讨外周血中性粒细胞/淋巴细胞比值(NLR)、淋巴细胞/单核细胞比值(LMR)及血小板/淋巴细胞比值(PLR)在非小细胞肺癌(NSCLC)诊断中的价值。方法分析83例NSCLC患者和60例作为健康对照者的NLR、LMR、PLR,观察不同病理类型及TNM分期的NSCLC患者PLR差异,运用受试者工作特征(ROC)曲线评价PLR能否作为NSCLC诊断及鉴别病理类型的临床指标。结果与健康体检者相比较,NSCLC患者PLR值明显升高,鳞癌患者PLR明显高于腺癌患者。而NLR、LMR在NSCLC患者和健康体检者间无显著性差异。ROC曲线结果显示,采用PLR诊断NSCLC的曲线下面积为0.633,敏感性为0.59,特异性为0.61,界值为115.00;鉴别鳞癌与腺癌的曲线下面积为0.608,敏感性为0.61,特异性为0.66,界值为126.51。Spearman相关性分析结果显示,NSCLC患者PLR与TNM分期呈正相关性。结论 PLR值具有初步诊断肺癌、鉴别TNM分期及病理类型的价值。
出处 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2016年第12期1683-1686,共4页 Chinese Journal of Cellular and Molecular Immunology
基金 国家自然科学基金(81171662) 安徽省卫生计生委科研计划项目(2016QK014)
  • 相关文献

参考文献2

二级参考文献26

  • 1Francesco Colotta,Paola Allavena,Antonio Sica,Cecilia Garlanda,Alberto Mantovani.Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis . 2009 被引量:2
  • 2Coussens LM,Werb Z.Inflammation and cancer. Nature . 2002 被引量:3
  • 3Tadahiro Nozoe,Mayuko Kohno,Tomohiro Iguchi,Emiko Mori,Takashi Maeda,Akito Matsukuma,Takahiro Ezaki.The prognostic nutritional index can be a prognostic indicator in colorectal carcinoma[J]. Surgery Today . 2012 (6) 被引量:3
  • 4Tadahiro Nozoe,Mizuki Ninomiya,Takashi Maeda,Akito Matsukuma,Hideaki Nakashima,Takahiro Ezaki.Prognostic nutritional Index: A tool to predict the biological aggressiveness of gastric carcinoma[J]. Surgery Today . 2010 (5) 被引量:1
  • 5Young Wha Koh,Hyo Jeong Kang,Chansik Park,Dok Hyun Yoon,Shin Kim,Cheolwon Suh,Heounjeong Go,Ji Eun Kim,Chul-Woo Kim,Jooryung Huh.The Ratio of the Absolute Lymphocyte Count to the Absolute Monocyte Count Is Associated with Prognosis in Hodgkin’s Lymphoma: Correlation with Tumor-Associated Macrophages[J]. The Oncologist . 2012 (6) 被引量:2
  • 6Tomokazu Kishiki,Tadahiko Masaki,Hiroyoshi Matsuoka,Takaaki Kobayashi,Yutaka Suzuki,Nobutsugu Abe,Toshiyuki Mori,Masanori Sugiyama.Modified Glasgow prognostic score in patients with incurable stage IV colorectal cancer[J]. The American Journal of Surgery . 2013 (2) 被引量:1
  • 7Wenzhuo He,Chenxi Yin,Guifang Guo,Chang Jiang,Fang Wang,Huijuan Qiu,Xuxian Chen,Ruming Rong,Bei Zhang,Liangping Xia.Initial neutrophil lymphocyte ratio is superior to platelet lymphocyte ratio as an adverse prognostic and predictive factor in metastatic colorectal cancer[J]. Medical Oncology . 2013 (1) 被引量:2
  • 8Youngjoo Lee,Sun Hye Kim,Ji-Youn Han,Heung Tae Kim,Tak Yun,Jin Soo Lee.Early neutrophil-to-lymphocyte ratio reduction as a surrogate marker of prognosis in never smokers with advanced lung adenocarcinoma receiving gefitinib or standard chemotherapy as first-line therapy[J]. Journal of Cancer Research and Clinical Oncology . 2012 (12) 被引量:2
  • 9Kenei Furukawa,Hiroaki Shiba,Koichiro Haruki,Yuki Fujiwara,Tomonori Iida,Yoshinobu Mitsuyama,Masaichi Ogawa,Yuichi Ishida,Takeyuki Misawa,Katsuhiko Yanaga.The Glasgow prognostic score is valuable for colorectal cancer withboth synchronous and metachronous unresectable liver metastases[J]. Oncology Letters . 2012 (2) 被引量:1
  • 10Michael J. Proctor,David S. Morrison,Dinesh Talwar,Steven M. Balmer,Colin D. Fletcher,Denis St.J. O’Reilly,Alan K. Foulis,Paul G. Horgan,Donald C. McMillan.A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study[J]. European Journal of Cancer . 2011 (17) 被引量:2

共引文献446

同被引文献90

引证文献12

二级引证文献93

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部