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脊髓内室管膜瘤影像学表现及临床病理研究 被引量:5

MRI features of spinal ependymoma and clinical pathological analysis
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摘要 目的:探讨脊髓内室管膜瘤的影像学表现、诊断和病理特点。方法:回顾性分析经显微神经外科手术治疗且术后病理证实为脊髓内室管膜瘤52例患者的临床资料。结果:脊髓内室管膜瘤主要以慢性疼痛为首发症状,可伴有感觉及运动功能障碍。MRI常表现为T1WI序列呈低信号或等信号,T2WI序列呈高信号。增强后呈不均匀强化。常伴有特征性"帽征"。镜下肿瘤细胞呈特征性菊形团,GFAP染色常呈阳性。结论:脊髓内室管膜瘤与其他脊髓肿瘤相比缺少特异性临床症状及影像学表现,临床主要依靠病理学诊断。 Objective:Spinal ependymoma has low incidence rate but was associated with difficult diagnosis op-tions. This paper discusses the imaging findings, diagnosis and pathology of spinal ependymoma. Methods: Retro-spective study of 52 cases with pathological diagnosis for patients with spinal ependymoma. who underwent surgical treatment in our department. Results: The commonly clinical manifestation was chronic pain. On MRI spinal ependymomas were centrally located. On T1WI ependymomas appear hypo-or isointense and hyperintense on T2. Ependymomas appear heterogeneous enhancing with contrast. Eqpendymoma has distinctive chrysanthemum-like ap-pearance under the microscope and GFAP( + ). Conclusion: The clinical manifestations of spinal ependymomas are difficult to distinguish from other intramedullary tumors. Diagnosis mostly depends on Pathology and immunohisto- chemistry.
出处 《陕西医学杂志》 CAS 2017年第2期188-189,192,共3页 Shaanxi Medical Journal
基金 国家自然科学基金资助项目(81101917/H1618) 辽宁省临床能力建设项目(LNCCC-D05-2015)
关键词 脊髓 室管膜瘤 磁共振成像 病理学 Spinal Ependymoma Magnetic resonance imaging Pathology
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