摘要
1例75岁男性患者因发热、尿频、尿急、腰痛、肌肉酸痛、乏力，被诊断为泌尿系感染后第3天实验室检查示CK 14 190 U/L，CK-MB 204 U/L,诊断为横纹肌溶解症。患者因高脂血症、动脉粥样硬化、冠心病规律服用阿托伐他汀钙（20 mg/d）超过10年。考虑患者的横纹肌溶解症与长期服用阿托伐他汀钙复加尿路感染有关。停用阿托伐他汀钙，给予抗感染、补液、纠正电解质紊乱等治疗7 d后，患者尿路感染症状消失，无不适主诉，实验室检查示CK 472 U/L，CK-MB 4 U/L，尿常规检查无异常。约1个月后复查，CK 52 U/L，CK-MB 5 U/L。
A 75-year-old man with symptoms of fever, frequent and urgent urination, backache, muscle aches, and fatigue was diagnosed as urinary track infection. The results of laboratory test reported three days after the diagnosis showed the following volumes： （CK） 14 190 U/L, CK-MB 204 U/L. He was diagnosed as rhabdomyolysis. The patient had been regularly taking atorvastatin （20 mg/d） for over 10 years due to his hyperlipidemia, atherosclerosis, and coronary heart disease. The rhabdomyolysis was considered to be related to long-term use of atorvastatin complicated with urinary tract infection. Atorvastatin was discontinued immediately and the treatments including anti-infection, fluid infusion, and correction of electrolyte imbalance were given. Seven days after the treatments, the patient′s symptoms of urinary track infection were disappeared and he had no any complaints. The results of laboratory test showed CK 472 U/L,CK-MB 4 U/L, and the urine routine examination showed no abnormal results. The results of follow-up about one month later showed CK 52 U/L,CK-MB 5 U/L.
出处
《药物不良反应杂志》
CSCD
2016年第6期459-460,共2页
Adverse Drug Reactions Journal
