摘要
目的:观察胺碘酮在急性心肌梗死院前急救中的临床疗效。方法:将90例急性心肌梗死患者,依据院前急救治疗方式不同分为观察组和对照组,每组各45例,两组均进行吸氧、取平卧位或半卧位休息、皮下注射吗啡止痛等基础性急救,对照组患者应用利多卡因抗心律失常,观察组患者应用胺碘酮进行抗心律失常,两组治疗周期为3 d,观察两组患者预后情况,比较两组患者平均除颤次数及住院天数,并进行血气指标分析。结果:治疗结束后,两组患者Pa O2、Pa CO2等动脉血气指标值均不同程度改善,其中,观察组上述指标改善尤为显著,与治疗前及同期对照组比较,差异均具有统计学意义(P<0.05);观察组患者抢救成功率显著高于对照组,心肌梗死复发率显著低于对照组,差异有统计学意义(P<0.05);观察组患者平均除颤次数及住院天数均显著低于对照组,差异有统计学意义(P<0.05)。结论:以胺碘酮为急救药物,对急性心肌梗死患者进行院前急救,可显著改善患者预后水平及临床症状,疗效良好,值得临床推广应用。
Objective To observe the clinical effect of amiodarone pre-hospital emergency treatment of patients with acute myocardial infarction（ AMI）. Method 90 patients with AMI were randomly divided into observation group and control group,45 cases in each group. Two groups were treated with basic emergency treatment. The patients in the control group were treated with lidocaine,and the patients in the observation group were treated with amiodaronet for 3 days. The prognosis of patients in the two groups,the average defibrillation times and hospitalization time,the changes of the blood gas indicators were compared after the treatment. Results After treatment,the blood gas indicators of patients in the two groups improved in different degrees,and the observation group improved more significantly than the control group（ P〈 0. 05）;the rescue success rate of the observation group was significantly higher than control group,recurrence of myocardial infarction the rate was significantly lower than the control group（ P〈 0. 05）;the average number of patients observed defibrillation and hospitalization days were significantly lower than the control group（ P〈 0. 05）. Conclusion Taking amiodarone as emergency medicine,pre-hospital emergency treatment for patients with AMI can significantly improve the prognosis and clinical symptoms,and has good curative effect,which is worthy of clinical application.
出处
《吉林医学》
CAS
2017年第2期223-224,共2页
Jilin Medical Journal
关键词
胺碘酮
急性心肌梗死
预防性应用
Amiodarone
Acute myocardial infarction
Prophylactic application
