摘要
目的探讨替罗非班引起的过敏反应和血小板减少症的诊断和处理策略。方法分析上海市第一人民医院的替罗非班引起的过敏反应和血小板减少症1例,为如何防治替罗非班引起的过敏反应和血小板减少症提供建议。结果急性非ST段抬高型心肌梗死患者使用替罗非班24 h内出现过敏反应和重度血小板減少,停药后血小板计数(PLT)逐渐恢复到参考范围,所以诱发该患者血小板减少症最可能的药物为替罗非班。结论替罗非班可引起过敏反应和血小板减少症,应尽早检测PLT变化并及时处理。
Objective To explore the diagnosis and treatment of allergic reactions and thrombocytopenia syndrome caused by tirofiban. Methods We analyzed 1 patient with allergic reaction and thrombocytopenia syndrome caused by tirofiban in Shanghai General Hospital, and provided suggestions for the prevention of allergic reaction and thrombocytopenia syndrome caused by tirofiban. Results Within the use of tirofiban 24 h, patients with acute non ST segment elevation myocardial infarction occurred allergic reactions and severe thrombocytopenia. After withdrawal, the platelet count （ PLT） gradually recovered to the reference range. So the most likely drug causing thrombocytopenia syndrome was tirofiban. Conclusion Tirofiban can cause allergic reactions and thrombocytopenia syndrome, so we should detect the change of PLT as soon as possible and deal with it in time.
出处
《中国全科医学》
CAS
CSCD
北大核心
2016年第B12期470-471,共2页
Chinese General Practice
