摘要
【目的】分析(和比较)胶囊内镜在糖尿病胃轻瘫(diabetic gastroparesis,DGP)患者中胃通过时间(gastric transit time,GTT)及小肠通过时间(small intestinal transit time,SITT)与正常体检人群中的差别及相关性,并探讨其应用价值及相关因素的影响。【方法】将2015年1月至2016年7月间来院的30例糖尿病胃轻瘫患者作为DGP组,27例正常体检者作为对照组,使用胶囊内镜,记录其GTT和SITT,分析比较两组间数据差别,并分别对两组中GTT与SITT的相关性以及DGP组中病程、糖化血红蛋白(Hb A1c)、年龄等相关因素与GTT及SITT相关性进行研究。【结果】胶囊内镜在糖尿病胃轻瘫患者中的GTT明显长于正常体检人群(P<0.05),而在SITT上糖尿病胃轻瘫患者也长于正常体检人群,但并不存在明显的统计学差异,两组中GTT与SITT均不存在相关性;DGP组中病程与GTT及SITT均存在正相关性,Hb A1c与GTT存在正相关性,与SITT不存在相关性,年龄与GTT和SITT均不存在相关性。【结论】胶囊内镜在糖尿病胃轻瘫患者的GTT与正常人群间存在明显差异,可用于糖尿病胃轻瘫的诊断,两组中GTT与SITT无相关性,糖尿病胃轻瘫患者的病程和Hb A1c水平对胶囊内镜的GTT存在正相关性,病程与SITT同时存在正相关性。
[Objective] To analyze （and compare） the difference and correlation of gastric transit time （GTr） and small intestinal transit time （SITY） via capsule endoscopy between patients with diabetic gastroparesis and people undergoing the health examination, and explore the application value and the effect of related factors. [Methods] A total of 30 patients with diabetic gastroparesis in our hospital were selected from January 2015 to July 2016 and divided into the I）GP group, while 2？ people undergoing the health examination were divided into the control group. GTI＂ and SITI＂ were recorded via capsule endoscopy. The difference of data was analyzed and compared between the two groups. The correlation between GTT and SITI＂ was studied. In the DGP group, the correlation of GTT and SIlT with some factors including duration of disease, glycosylated hemoglobin Alc （HbAlc）, age was also studied. [Results] GTT of capsule endoscopy in patients with diabetic gastroparesis was significantly longer than that in normal people （P〈 0.05）. Although SITT in patients with diabetic gastroparesis was also longer than that in normal people, there was no statistical difference between the two groups. There was no correlation between GTr and SITT in the two groups. In the DGP group, the correlation of GTT and SITT with duration of disease was positive. There was also positive correlation between HbAlc and GRIT, but no correlation between HbAlc and SITT. There was no correlation between age as well as GTT and SITT. [Conclusion ] GTT of capsule endoscopy in patients with diabetic gastroparesis is obviously different from that in normal people. Therefore it can be used in the diagnosis for diabetic gastroparesis. There is no correlation between GTT and SITT in the two groups. In the patients with diabetic gastroparesis, duration of disease and HbAlc level are positively correlated with GTT, and duration of disease is also positively correlated with SITT.
作者
杨海波
巨莉
张天先
YANG Hai-bo JU Li ZHANG Tian-xian(Department of Gastroenterology, Qinghai Provincial Crops Hospital of PAP, Xining 810000, China)
出处
《武警后勤学院学报（医学版）》
CAS
2016年第11期894-898,共5页
Journal of Logistics University of PAP（Medical Sciences）
关键词
胶囊内镜
糖尿病
胃轻瘫
胃通过时间
小肠通过时间
Capsule endoscopy
Diabetes mellitus
Gastroparesis
Gastric transit time
Small intestinal transit time
