摘要
先天性低通气综合征，也称 Ondine′s 诅咒，是以睡眠低通气及对高碳酸血症及低氧的低反应性为特征的疾病。这种紊乱通常合并非自主神经功能的神经障碍以及胚胎细胞形成脊髓的发育异常。本文将对该疾病发病机制、临床症状、诊断、治疗以及预后的最新进展作一综述。
Congenital central hypoventilation syndrome,also known as “Ondine′s curse”,is charac-terized by hypoventilation during sleep and impaired ventilatory responses to hypercapnia and hypoxemia. This disorder is associated with a malfunction of the nerves that control involuntary body functions and abnor-mal development of early embryonic cells that form the spinal cord. This review summarized the latest pro-gression in the pathogenesis,clinical symptoms,diagnosis,treatment and prognosis.
作者
赵芳萍
石静云
Zhao Fangping Shi Jingyun(Department of Neonatology , Gansu Provincial Maternity and Child-Care Hospital, Lanzhou 730050, Chin)
出处
《中国小儿急救医学》
CAS
2016年第12期852-855,共4页
Chinese Pediatric Emergency Medicine
关键词
先天性低通气综合征
发病机制
临床症状
诊断
治疗
预后
Congenital central hypoventilation syndrome
Pathogenesis
Clinical symptoms
Diag-nosis
Treatment
Prognosis
