摘要
Objective: To observe the clinical efficacy of umbilicus application with Chinese medicine in treating children's chronic diarrhea due to food intolerance and the value of healthy diet education. Methods: Eighty kids with chronic diarrhea due to food intolerance were recruited from multiple centers and divided by using the random number table into a treatment group of 40 cases and a control group of 40 cases. For both groups, based on the level of serum food-specific immunoglobulin G(Ig-G), the patients were given unified diet following the healthy diet guidance: safe, alternate, and forbidden, while the treatment group was additionally given umbilicus application with Chinese medicine. The therapeutic efficacy and symptom score of traditional Chinese medicine(TCM) were observed and compared respectively after 1-week, 2-week, 4-week, and 12-week treatment. Results: The diarrhea symptoms and coupled symptoms scores dropped significantly in the two groups after treatment( all P〈0.05), and the inter-group comparisons also showed statistical significances(P〈0.05). The total effective rate was 97.5% in the treatment group versus 77.5% in the control group, and the inter-group difference was statistically significant(P〈0.05). Conclusion: The healthy diet guidance based on the food intolerance test is effective in helping treat diarrhea, while umbilicus application with Chinese medicine works better in treating diarrhea for kids with chronic diarrhea due to food intolerance and can significantly enhance the therapeutic efficacy.
目的:观察中药脐部贴敷对食物不耐受型儿童慢性腹泻患者的临床疗效及饮食健康教育的价值。方法:将来自多中心的80例食物不耐受型儿童慢性腹泻患者根据随机数字表分为治疗组40例和对照组40例。两组均根据患儿血清中食物特异性Ig G抗体浓度,分别采取统一的"安全进食"、"轮替"、"忌食"的健康饮食指导,治疗组患儿给予中药脐部贴敷治疗。治疗1星期、2星期、4星期及12星期后观察并比较两组疗效及中医症状评分变化。结果:治疗后两组患者的症状评分均明显下降,与本组治疗前有统计学差异(均P<0.05),组间差异亦具有统计学意义(P<0.05)。对照组总有效率为77.5%,治疗组总有效率为97.5%,两组总有效率差异有统计学意义(P<0.05)。结论:根据食物不耐受检测结果对患儿进行健康饮食指导止泻有效,中药脐部贴敷对食物不耐受型儿童慢性腹泻具有更好的止泻作用,可显著提高疗效。
作者
Shen Jian
Chen Jian-jie
Chen Li
Zhang Bi-meng
Zhao Jun
Ye Qing-yan
Kong Ling-wan
沈健;陈建杰;陈黎;张必萌;赵鋆;叶青艳;孔令万;洪珏(译)(Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;Shanghai Baoshan District Hospital of Integrated Chinese and Western Medicine, Shanghai 201900, China;Shanghai First People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China;不详)
基金
supported by the Key Special Program of Science and Technology During the National Twelfth Five-year Plan(No.2012ZX10005004-003)
National Natural Science Foundati on of China(No.81302924)
Program of Shanghai Science and Technology Committee(No.15401971100)
Special Plan of Shanghai Chinese Medicine Experts(No.ZY3-RCPY-3-1027)~~