摘要
目的探讨快速粪便钙卫蛋白(fecal calprotectin,FC)检测卡在评价活动期溃疡性结肠炎(ulcerative colitis,UC)患者病情中的作用。方法采集46例住院患者粪便标本,应用快速FC检测卡进行检测,同时对患者病情进行改良的Baron内镜下UC活动度分级、改良的Truelove和Witts分级、改良Mayo活动指数及蒙特利尔分级4个量表进行评分,根据患者检测卡结果及病情评分分布情况,将患者按量表分为轻、中-重度两组,分别与检测卡结果列出四格表进行χ2检验。结果 4种量表评定的轻、中-重度与FC检测卡所得结果的阴性、阳性分布相比,差异无统计学意义(P>0.05)。结论应用临界值为50μg/g的快速FC检测卡可以评估UC患者病情处于轻度水平或中度以上水平。
Objective To investigate the effect of rapid fecal calprotectin（FC） test card in evaluation of patients with ulcerative colitis（UC）. Methods The fecal samples of 46 UC patients with clear diagnosis were collected. The rapid FC test card was used to get the calprotectin result,and the clinical presentation and endoscopy manifestation in the meantime were analyzed to gain the scores of 4 UC condition scales（included improved Baron endoscopic scale of UC activity,improved Truelove Witts scale,improved Mayo scale and Montreal classification）. After observing the distribution of patient numbers in the 4 scales and FC results,patients were classified into mild group and moderate-severe group according to the four types of classification standard. Each group of one classification method listed the FC result,and finally we got four four-fold tables. Statistical results were calculated through Chi-square test. Results There were no statistical differences between the distribution of FC negative samples and every mild group in all the 4 classification scales（P〉0. 05）. Conclusion Rapid FC test card（critical value 50 μg/g） can evaluate the UC patient activity degree in whether mild level or above.
出处
《胃肠病学和肝病学杂志》
CAS
2017年第1期56-58,共3页
Chinese Journal of Gastroenterology and Hepatology
