摘要
目的:评价头孢地尼与奥硝唑对盆腔炎患者免疫学和血液流变学的影响。方法:选取2014年9月—2015年12月间收治的盆腔炎患者84例作为本次的研究对象,采用计算机随机分组法将其分为常规组与观察组,每组42例;常规组患者给予奥硝唑治疗,观察组患者在常规组基础上加用头孢地尼治疗,评价两组患者治疗后的总有效率、免疫学和血液流变学的影响。结果:两组患者均接受为期2周的药物治疗,治疗前两组患者的IL-1、C-反应蛋白(CRP)、血浆黏度和红细胞压积值经组间比较其差异无统计学意义(P>0.05);治疗2周后观察组患者IL-1、C-反应蛋白、血浆黏度和红细胞压积值均优于常规组(P<0.05);治疗后的总有效率为92.86%高于常规组为69.05%(P<0.05)。结论:采用头孢地尼与奥硝唑治疗盆腔炎患者,能明显改善患者临床症状、免疫学和血液流变学各指标。
Objective： To evaluate the influence on immunology and hemorheology in patients with pelvic infection by using combination of cephalosporins with ornidazole. Methods： To choose 84 cases of patients with pelvic infection as the research object between September 2014 and December 2015, using the computer divided into normal group and observation group（42 cases in each group）. Routine group patients were given ornidazole treatment and observation group of patients based on the conventional treatment used cephalosporins, total effective rate of two groups of patients alter treatment and the influence of immunology and hemorheology were evaluted. Results： Two groups of patients accepted treatment for two weeks; two groups of patients before treatment of IL-1, C-reactive protein （CRP）, plasma viscosity and erythrocyte pressure product values have no obvious difference（P〉0.05）. Treatment for 2 weeks in the observation group of patients, IL-1, C-reactive protein, blood plasma viscosity and erythrocyte pressure product value were significantly better than those of the conventional group（P〈0.05）. After treatment the total effective rate was 92.86% higher than normal group 69.05% （P〈0.05）. Conclusion： Using cephalosporins and ornidazole treatment in patients with pelvic infection may obviously improve the clinical symptoms and immunology and hemorheology indexes.
出处
《抗感染药学》
2016年第6期1320-1322,共3页
Anti-infection Pharmacy
关键词
头孢地尼
奥硝唑
盆腔炎
免疫学
血液流变学
cephalosporins
ornidazole
pelvic infection
immunology
hemorhcology
