摘要
目的:观察以痿论治咽喉反流性疾病的临床疗效。方法:应用反流症状指数(RSI)与反流体征的量表(RFS)评估124例咽喉反流性疾病患者,随机分为两组,对照组口服质子泵抑制剂泮托拉唑钠肠溶胶囊40 mg日2次,试验组在对照组基础上口服补中益气汤加减,评估两组治疗前后RSI、RFS及唾液胃蛋白酶浓度。结果:两组治疗后RSI评分均低于治疗前,差异有统计学意义(P<0.05);两组治疗后RSI评分比较,差异有统计学意义(P<0.05)。两组治疗后RFS评分均低于治疗前,差异有统计学意义(P<0.05);两组治疗后RFS评分比较,差异无统计学意义(P>0.05),两组治疗后唾液胃蛋白酶浓度较治疗前均有下降,治疗后试验组与对照组比较,差异有统计学意义(P<0.05)。结论:以痿论治咽喉反流性疾病可降低RSI和RFS评分及唾液胃蛋白酶浓度。
Objective：To observe the clinical effect of paralysis theory on treating laryngopharyngeal reflux disease. Methods：Applicate RSI and RFS assessment of 124 cases of laryngopharyngeal reflux disease patients,were randomly assigned to two groups,the control group was given oral pantoprazole sodium enteric coated capsules 40 mg twice a day,the experimental group on the basis of the control group was given oral Buzhong Yiqi Decoction,evaluate before and after treatment in the two groups of RSI and RFS and salivary concentration of pepsin. Results：Two groups of RSI score after treatment was lower than that before treatment,the difference was statistically significant（P〈0.05）;RSI scores between the two groups after treatment,the difference was statistically significant（P〈0.05）. Two groups of RFS score after treatment was lower than that before treatment,the difference was statistically significant（P〈0.05）;RFS scores between the two groups after treatment,there was no statistically significant difference（P〉0.05）,the two groups after treatment of salivary concentration of pepsin were decreased compared with before treatment,after treatment in experimental group compared with control group,the difference was statistically significant（P〈0.05）. Conclusion：Paralysis theory treatment of laryngopharyngeal reflux disease can reduce the RSI and RFS score and pepsin concentration in saliva of flaccidity.
出处
《辽宁中医药大学学报》
CAS
2017年第1期114-116,共3页
Journal of Liaoning University of Traditional Chinese Medicine
基金
国家中医药管理局中医药标准化项目(ZYYS-2013[PJ18])
关键词
补中益气汤
咽喉反流
痿证
胃蛋白酶
Buzhong Yiqi Decoction
laryngopharyngeal reflux
paralysis
pepsin
