摘要
目的分析药店止泻药销售量与医院腹泻就诊病例数的相关性,评价止泻药销量作为食源性疾病间接监测指标的可行性。方法 2015年腹泻病例信息从上海市23家腹泻病例监测哨点医院的腹泻病监测系统收集,止泻药销售量采集自哨点医院区域内的某连锁药店530家门店的销售信息系统2014年全年销售量前10位且各门店均销售的止泻类非处方药物,采用Spearman秩相关分析两者的相关性。结果 2015年全年监测的止泻药销售量与哨点医院腹泻病例数时间变化趋势相近,1、7、8月均存在季节性高峰,这3个月的止泻药销售量分别为18 855、21 484、21 487盒,腹泻病例就诊数分别为3 647、2 977、3 518例。Spearman秩相关分析结果显示,各类止泻药销售量、合计销售量、含黄连素类药物合计销售量均与当日腹泻就诊病例数呈正相关(P<0.01)。其中复方木香小檗碱片的Spearman相关系数最大,为0.695。医院腹泻就诊病例数与前1、2、3、5及7 d的各类止泻药销售量均呈正相关(P<0.01),相关系数分别为0.630、0.597、0.503、0.579和0.564。结论上海市药店止泻药销售量与医院腹泻就诊病例数存在一定的相关关系,可考虑将前1~2 d的药店止泻药销售量作为医院腹泻患者就诊的预警指标。
Objective To learn the relationship between the sale volume of anti- diarrhea drugs and diarrhea cases,and to evaluate the possibility of using the sale volume of anti- diarrhea drugs as an indirect indicator of foodborne disease surveillance. Methods Collect data of sale volume of 10 kinds of anti- diarrhea drugs in Shanghai Pharmacy Company Limited and diarrhea cases of 23 sentinel hospitals in Shanghai in 2015,and correlation analysis was conducted. Results The variation trend of sale volume of anti- diarrhea drugs and diarrhea cases in sentinel hospitals were similar,and there were same peaks in summer and winter. Sale volume of 10 kinds of anti- diarrhea drugs correlated with diarrhea cases,and the Spearman correlation coefficient of compound ancklandia and berberine tablets was the highest and it reached 0. 695.The coefficient of the sum of ten kinds of anti- diarrhea drugs one or two days before diarrhea cases in sentinel hospitals was higher and reached 0. 630 and 0. 597. Conclusion Anti- diarrhea drugs sale volume were correlatd with diarrhea cases in sentinel hospitals in Shanghai. The sale volume of anti- diarrhea drugs one or two days before diarrhea cases in sentinel hospitals could be used as an indirect indicator of surveillance.
出处
《预防医学》
2017年第1期36-39,共4页
CHINA PREVENTIVE MEDICINE JOURNAL
关键词
药物销售量
止泻药
哨点医院
腹泻病例
相关性分析
Pharmacy sales
Anti-diarrhea drugs
Sentinel hospitals
Diarrhea cases
Correlation analysis
