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急性冠脉综合征患者口服抗血小板药物现状与展望 被引量:7

Current status and prospect of oral anti-platelet drugs for patients with acute coronary syndrome
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摘要 急性冠脉综合征(ACS)发生发展的实质是血栓事件,抗血小板治疗是ACS治疗的基石,阿司匹林联合氯吡格雷是经典的双联抗血小板治疗方案。新型P2Y12受体抑制剂(普拉格雷或替格瑞洛)与氯吡格雷相比在改善缺血和预后方面具有更多优势,但也增加了出血风险。本文拟对近几年ACS患者口服抗血小板药物治疗研究进展做一综述。 The essence of occurance and development of acute coronary syndrome (ACS) is the thrombotic events. The antiplatelet therapy is the cornerstone of ACS treatment. The combination of aspirin and clopidogrel is a classic dual anti-platelet therapy. The novel P2Y12 receptor inhibitor (prasugrel or tigriol), on the one hand, has more advantages in the improvement of ischemia and prognosis than clopidogrel does, but on the other hand it increases the risk of bleeding. The aim of this paper is to review the research progress in oral anti-platelet drugs therapy in ACS patients.
出处 《实用医院临床杂志》 2017年第1期26-29,共4页 Practical Journal of Clinical Medicine
关键词 急性冠脉综合征 抗血小板药物 P2Y12受体抑制剂 阿司匹林 Acute coronary syndrome Anti-platelet drugs P2Y12 receptor inhibitor Aspirin
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  • 1Tunstall-Pedoe H,Kuulasmaa K,Mhnen M,et al.Contribution of Trends in Survival and Coronar Y-Event Rates to Changes in Coronary Heart Disease Mortality:10-Year Results from 37 Who Monica Project Populations[J].Lancet,1999,353(9164):1547-1557. 被引量:1
  • 2Group WB.Toward a Healthy and Harmonious Life in China:Stemming the Rising Tide of Non-Communicable Diseases[N/OL].http://www.worldbank.org/en/news/feature/2011/07/26/towardhealth-harmonious-life-china-stemming-rising-tide-of-non-communi cable-diseases(accessed 27/03,2014)(Type of Medium),2011. 被引量:1
  • 3Tan GM,Lam YY,Yan BP.Novel Platelet ADP P2Y12 Inhibitors in the Treatment of Acute Coronary Syndrome[J].Cardiovasc Ther,2012,30(4):e167-173. 被引量:1
  • 4Balsano F,Rizzon P,Violi F,et al.Antiplatelet Treatment with Ticlopidine in Unstable Angina.A Controlled Multicenter Clinical Trial.The Studio Della Ticlopidina Nell'angina Instabile Group[J].Circulation,1990,82(1):17-26. 被引量:1
  • 5Cosmi B,Rubboli A,Castelvetri C,et al.Ticlopidine Versus Oral Anticoagulation for Coronary Stenting[J].Cochrane Database Syst Rev,2001(4):CD002133. 被引量:1
  • 6Leon MB,Baim DS,Popma JJ,et al.A Clinical Trial Comparing Three Antithrombotic-Drug Regimens after Coronary-Artery Stentin[J].New Engl J Med,1998,339(23):1665-1671. 被引量:1
  • 7Gent M,Donald Easton J,Hachinski V,et al.The Canadian American Ticlopidine Study(Cats)in Thromboembolic Stroke[J].Lancet,1989,333(8649):1215-1220. 被引量:1
  • 8Sabatine MS,Cannon CP,Gibson CM,et al.Addition of Clopidogrel to Aspirin and Fibrinolytic Therapy for Myocardial Infarction with St-Segment Elevation[J].New Engl J Med,2005,352(12):1179-1189. 被引量:1
  • 9Chen ZM,Jiang LX,Chen YP,et al.Addition of Clopidogrel to Aspirin in 45,852 Patients with Acute Myocardial Infarction:Randomised Placebo-Controlled Trial[J].Lancet,2005,366(9497):1607-1621. 被引量:1
  • 10Antman EM,Hand M,Armstrong PW,et al.2007 Focused Update of the Acc/Aha 2004 Guidelines for the Management of Patients with St-Elevation Myocardial Infarction:A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines:Developed in Collaboration with the Canadian Cardiovascular Society Endorsed by the American Academy of Family Physicians:2007 Writing Group to Review New Evidence and Update the Acc/Aha 2004 Guidelines for the Management of Patients with St-Elevation Myocardial Infarction,Writing on Behalf of the 2004 Writing Committee[J].Circulation,2008,117(2):296-329. 被引量:1

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