摘要
目的:研究脑梗死患者颈动脉粥样硬化斑块(CAP)及其对患者复发的影响。方法:选择从2014月1月至2015年12月在医院就诊的急性脑梗死(ACI)患者262例纳入本次研究,其中检出斑块组180例,未检出斑块组82例;初发患者213例,复发患者49例。随访3个月,对比各组患者的复发情况,分析患者斑块与脑梗死复发的关系,对比斑块组与无斑块组临床相关指标,分析影响斑块形成的危险因素。结果:斑块组的复发率高于无斑块组,复发时间短于无斑块组,差异有统计学意义(P<0.05)。非易损斑块组的复发率低于易损斑块组,复发时间长于易损斑块组,差异有统计学意义(P<0.05)。初发患者及复发患者的斑块均以BIF更为多见,且左侧较右侧更多,差异有统计学意义(P<0.05)。斑块组的年龄、高血压、糖尿病以及高血脂的比例高于无斑块组,差异有统计学意义(P<0.05)。依据Logistic回归分析法评价发现,影响斑块形成的危险因素有年龄和高血压,以及糖尿病和高血脂。结论:CAP可导致ACI患者更易复发,特别是易损斑块者,更应引起临床关注。
Objective：To study carotid atherosclerotic plaque in patients with cerebral infarction and its effect on patients with recurrence. Methods：262 patients with acute cerebral infarction （ ACI） admitted in the hospital from January 2014 to December 2015 were selected as objects, the detection of plaque group 180 ca-ses, 82 cases were not detected in plaque group;213 cases of primary patients, 49 cases of patients with re-currence. After 3 months of follow-up, the recurrence of patients were compared, analysis of the relationship between plaque and cerebral infarction recurrence, compared with plaque group and no plaque group related clinical indicators, analysis of risk factors for plaque formation. Results：The recurrence rate of plaque group was significantly higher than that of non plaque group, the recurrence time was significantly shorter than non plaque group, the difference was statistically significant （ P 〈 0.05） . The non vulnerable plaque group relapse rate was significantly lower than that of vulnerable plaque group, the recurrence time was significantly longer than the vulnerable plaque group, the difference was statistically significant （ P〈0.05） . Patients with primary and recurrent patients with BIF plaques were more common, and more in left than in the right side, the differ-ence was statistically significant （ P〈0.05） . The age, high blood pressure, diabetes and high blood lipids of the plaque group were significantly higher than those without plaque group, the difference was statistically sig-nificant （P〈0.05）. According to the Logistic regression analysis, the risk factors of plaque formation were age and hypertension, diabetes and high blood fat. Conclusion：CAP can lead to ACI patients more prone to relapse, especially vulnerable plaque, but also should cause clinical attention.
出处
《河北医学》
CAS
2016年第12期1939-1942,共4页
Hebei Medicine
基金
福建省自然科学基金项目编号
(编号:2016J01659)
关键词
脑梗死
颈动脉
粥样硬化斑块
Cerebral infarction
Carotid artery
Atherosclerotic plaque
