摘要
研究了丹参脂溶性化学成分.采用硅胶柱色谱,Sephadex LH-20和HPLC等色谱技术进行分离和纯化,根据波谱数据对化合物进行结构鉴定.从丹参的乙醇提取物中分离得到11个化合物,分别鉴定为2,3-反式-4,5-顺式-二烯-6-羰基硬脂酸(1)、丹参螺旋缩酮内酯(2)、丹参酮Ⅰ(3)、丹参酮ⅡA(4)、二氢丹参酮Ⅰ(5)、二氢异丹参酮Ⅰ(6)、异隐丹参酮(7)、丹参酸甲酯(8)、弥罗汉酚(9)、Sibiriqninone A(10)、Sibiriqninone B(11).化合物1为新化合物,命名为2,3-反式-4,5-顺式-二烯-6-羰基硬脂酸.
Aim To study the chemical constituents from 95% ethanol extract of Radix salviae miltiorrhizae. Methods The compounds were isolated and purified by silica gel, Sephadex LH-20 column chromatography, and HPLC.The structures of the compounds were identified on the basis of spectral methods.Results Eleven compounds were isolated and purified from the 95% ethanol extract of radix salviae miltiorrhizae and identified as：2, 3-trans-4,5- cis- diene - 6- carbonyl stearic acid （ 1 ）, danshenspiroketallactone （ 2 ）, tanshinone Ⅰ （ 3 ）, tanshinone Ⅱ A （ 4）, dihydrotanshinone Ⅰ （ 5 ）, dihydroisotanshinone （ 6 ）, isocryptotanshinone （ 7 ）, methyl tanshinonate （ 8）, ferruginol （ 9）, sibiriqninone A （ 10）, and sibiriqninone B （ 11 ）. Conclusion Compound 1 is a new compound named 2,3-trans-4,5-cis-diene-6-carbonyl stearic acid.
出处
《云南大学学报（自然科学版）》
CAS
CSCD
北大核心
2017年第1期115-119,共5页
Journal of Yunnan University(Natural Sciences Edition)
关键词
丹参
脂溶性成分
化学成分
新共轭二烯酸
Radix salviae miltiorrhiza
liposoluble constituents
chemical constituent
new conjugated dienoic acid
