摘要
目的研究血尿酸水平及饮酒与帕金森病发病风险的相关性。方法采用回顾性研究方法,选取2013年1月至2015年12月我院收治的帕金森病患者128例作为研究组,同期健康体检者117例作为对照组,分析帕金森病发病风险的影响因素。结果升高的血尿酸水平能降低帕金森病发病风险(OR=0.38,95%CI:0.26~0.61),以性别分组后,仍存在这一相关性。不饮酒人群中,血尿酸水平升高,帕金森病的发病风险降低(OR=0.43,95%CI:0.36~0.75)。结论高尿酸水平能降低帕金森病的发病风险,饮酒可能改变了其对帕金森病的保护作用。
Objective To investigate the relationship between serum uric acid levels, drinking and the occurrence of Parkinson＇s disease. Methods A retrospective study was carried out, one-hundred and twenty-eight cases of patients with parkinson＇s disease in our hospital from January, 2013 to December 2015 were selected as the study group, and 117 cases of health subjects at the same term were enrolled as the control group. The risk factors for parkinson disease were analyzed. Results Elevating serum uric acid levels reduced the risk of Parkinson＇s disease （OR=0.38, 95%CI： 0.26-0.61）, and this correlation still existed when the people were grouped and analyzed by sex. In no drinking people, the elevation of serum uric acid levels reduced the risk of parkinson＇s disease （OR=0.43, 95%CI： 0.36-0.75）. Conclusion High uric acid levels can reduce the risk of Parkinson＇s disease, drinking may affect its protective effect on the disease of Parkinson.
出处
《临床医学研究与实践》
2017年第2期4-5,7,共3页
Clinical Research and Practice
关键词
尿酸水平
帕金森病
饮酒
uric acid levels
parkinson＇s disease
drinking
