摘要
目的分析甲泼尼龙冲击疗法应用在急性脊髓炎治疗中的有效性。方法 80例急性脊髓炎患者,按随机数字法分为实验组和对照组,各40例。实验组采用甲泼尼龙冲击疗法治疗,对照组采用常规治疗。比较两组治疗总有效率及脊髓神经功能恢复情况。结果实验组患者治疗显效32例,有效6例,无效2例,治疗总有效率为95.0%(38/40);对照组患者治疗显效20例,有效9例,无效11例,治疗总有效率为72.5%(29/40),实验组患者治疗总有效率高于对照组患者,差异具有统计学意义(P<0.05)。实验组肌力改善2级时间为(4.8±1.2)d,排尿恢复时间为(9.4±2.6)d,自行下地行走时间为(14.3±1.4)d;对照组肌力改善2级时间为(9.7±1.9)d,排尿恢复时间为(18.3±2.7)d,自行下地行走时间为(22.3±2.6)d。实验组肌力改善2级时间、排尿恢复时间、自行下地行走时间均短于对照组,差异具有统计学意义(P<0.05)。结论甲泼尼龙冲击疗法可改善急性脊髓炎患者的脊髓神经功能,疗效肯定,临床推广价值更高。
Objective To analyze effectiveness by methylprednisolone shock therapy applied in the treatment of acute myelitis. Methods A total of 80 patients with acute myelitis were divided by random number table into experimental group and control group, with 40 cases in each group. The experimental group received methylprednisolone shock therapy, and the control group received conventional treatment. Comparison was made on total effective rate and spinal neural function recovery between the two groups. Results The experimental group had 32 excellent cases, 6 effective cases and 2 ineffective cases, with total effective rate as 95.0% （38/40）. The control group had 20 excellent cases, 9 effective cases and 11 ineffective cases, with total effective rate as 72.5% （29/40）. The experimental group had higher total effective rate than the control group, and the difference had statistical significance （P〈0.05）. The experimental group had grade 2 myodynamia improvement time as （4.8± 1.2） d, urination recovery time as （9.4 ± 2.6） d, independent off-bed walk time as （14.3 ± 1.4） d. The control group had grade 2 myodynamia improvement time as （9.7 ± 1.9） d, urination recovery time as （18.3± 2.7） d, independent off-bed walk time as （22.3 ± 2.6） d. The experimental group had all shorter grade 2 myodynamia improvementtime, urination recovery time and independent off-bed walk time than the control group, and the difference had statistical significance （P〈O.05）. Conclusion Methylprednisolone shock therapy can improve spinal neural function in acute myelitis patients with affirmative effect. It contains high value for clinical promotion.
出处
《中国实用医药》
2016年第32期59-61,共3页
China Practical Medicine
关键词
甲泼尼龙
急性脊髓炎
冲击疗法
有效性
Methylprednisolone
Acute myelitis
Shock therapy
Effectiveness
