摘要
目的比较球囊探查加选择性支气管封堵术与凝血酶胸膜腔粘连术治疗难治性气胸的疗效。方法选取该院呼吸内科2006-01-2016-04经胸腔穿刺及胸腔置管引流术、负压吸引等措施7-14 d后自发性气胸仍未愈合的难治性气胸患者71例,接受球囊探查加选择性支气管封堵术26例,凝血酶胸膜腔粘连术45例（两法重合4例）,比较两种方法疗效及不良反应。结果球囊探查加封堵术组成功率为69.2%（18/26）,凝血酶胸膜腔粘连术组成功率为48.9%（22/45）;球囊探查加封堵术组有效率为84.6%（22/26）,凝血酶胸膜腔粘连术组有效率为71.1%（32/45）。球囊探查加选择性支气管封堵术组疗效优于凝血酶胸膜腔粘连术组,差异具有统计学意义（P〈0.05）。结论两种方法治疗难治性气胸均安全、有效,尤其适用于全身情况差、肺功能明显减退以及不愿接受手术者,但球囊探查加选择性支气管封堵术疗效优于凝血酶胸膜腔粘连术。
Objective To compare the curative effects between transbronchoscopic balloon detection（ TBD）plus selective bronchus occlusion（ SBO） and thrombin pleural adhesions（ TPA） in the treatment of intractable pneumothorax. Methods Seventy-one partents in our department who received needle thoracocetesis and chest tube drainage for 7 - 14 days but failed to close the spontaneous pneumothorax were collected and were treated with TBD plus SBO（ TBD ＋ SBO group,n = 26） or thrombin pleural adhesions（ TPA group,n = 45） in the treatment of intractable pneumothorax. The curative effects and adverse reactions were compared between the two groups. Results The successful rate was 69. 2%（ 18 /26） in TBD ＋ SBO group,and 48. 9%（ 22 /45） in TPA group. The effective rate of TBD ＋SBO group was 84. 6%（ 22 /26）,and the effective rate of TPA group was 71. 1%（ 32 /45）. The curative effect of TBD ＋ SBO group was better than that of the TPA group（ P〈0. 05）. Conclusion Both TPA and TBD plus SBO are safe and effective in the treatment of intractable pneumothorax particularly for the patients with poor conditions,or for those with decreased lung function and for those who are reluctant to accept the surgery.
出处
《中国临床新医学》
2016年第12期1122-1125,共4页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
关键词
气胸
封堵术
凝血酶
胸膜腔粘连术
Pneumothorax
Bronchus occlusion
Thrombin
Pleural adhesions
